Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16985193 | 0.87 | ALDH1A1 (0.43) | MAOAALDH1A1HPGDGAAKDM4E | |
| SCHEMBL16985192 | 0.80 | MAOA (0.52) | MAOAALDH1A1HPGDGAAKDM4E | |
| SCHEMBL11842576 | 0.75 | XDH (0.63) | XDHBCHEACHE | |
| SCHEMBL14913063 | 0.73 | CA12 (0.47) | CA12CA1CA9ALDH1A1GAA | |
| SCHEMBL29116847 | 0.71 | AGER (0.68) | AGERCA12CA1CA9MAOA | |
| SCHEMBL16296942 | 0.71 | ALDH1A1 (0.49) | AGERCA12CA1CA9ALDH1A1 | |
| SCHEMBL1752667 | 0.70 | ALDH1A1 (0.70) | CA12CA1CA9MAOBALDH1A1 | |
| SCHEMBL3950391 | 0.70 | ALDH1A1 (0.68) | AGERCA12CA1CA9ALDH1A1 | |
| SCHEMBL660817 | 0.70 | ALDH1A1 (0.80) | AGERCA12CA1CA9MAOA | |
| SCHEMBL16603989 | 0.70 | AGER (1.00) | AGERCA12CA1CA9MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10253185-B2 | Fluorogenic pH-sensitive dyes and their methods of use (II) | Life Technologies Corporation (US) | 2019-04-09 | — | — | US | disclosed |
| US-20170145214-A1 | FLUOROGENIC PH-SENSITIVE DYES AND THEIR METHODS OF USE (II) | Life Technologies Corporation | 2017-05-25 | — | — | US | disclosed |
| US-20170145214-A1 | FLUOROGENIC PH-SENSITIVE DYES AND THEIR METHODS OF USE (II) | Life Technologies Corporation | 2017-05-25 | — | — | US | disclosed |
| US-9599622-B2 | Fluorogenic pH-sensitive dyes and their methods of use (II) | Life Technologies Corporation (US) | 2017-03-21 | — | — | US | disclosed |
| US-9599622-B2 | Fluorogenic pH-sensitive dyes and their methods of use (II) | Life Technologies Corporation (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150241438-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use | Life Technologies Corporation | 2015-08-27 | — | — | US | disclosed |
| US-20150241438-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use | Life Technologies Corporation | 2015-08-27 | — | — | US | disclosed |
| US-20150218379-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use (II) | Life Technologies Corporation | 2015-08-06 | — | — | US | disclosed |
| US-20150218379-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use (II) | Life Technologies Corporation | 2015-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10253185-B2 | Fluorogenic pH-sensitive dyes and their methods of use (II) | ALPG, XDH, ASAH2 | AGER 1836/4885CA12 328/4885CA1 204/4885 |
| US-20150241438-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use | ALPG, XDH, HEXD | AGER 1464/4885CA12 519/4885CA1 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.