Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2876560 | 0.94 | HPGD (0.37) | HPGDPOLBALDH1A1CES2CES1 | |
| SCHEMBL17028596 | 0.91 | CES2 (0.37) | HPGDPOLBALDH1A1CES2CES1 | |
| SCHEMBL9085983 | 0.82 | HTT (0.36) | HPGDPOLBCES2CES1GSK3B | |
| SCHEMBL29134942 | 0.78 | HPGD (0.33) | HPGDPOLBALDH1A1CES2CES1 | |
| SCHEMBL23878712 | 0.75 | HCAR3 (0.35) | ALDH1A1DAOSMN1; SMN2 | |
| SCHEMBL17028581 | 0.74 | HPGD (0.32) | HPGDPOLBALDH1A1CES2CES1 | |
| SCHEMBL24397864 | 0.71 | DAO (0.39) | DAOSMN1; SMN2 | |
| SCHEMBL9085747 | 0.70 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17028541 | 0.70 | SLC6A2 (0.35) | HPGDPOLBALDH1A1CES2CES1 | |
| SCHEMBL24036139 | 0.69 | DAO (0.36) | HPGDPOLBALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12377077-B2 | Methods and formulations to treat mitochondrial dysfunction | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-08-05 | — | — | US | disclosed |
| CN-113347972-B | Methods and formulations for treating mitochondrial dysfunction | 利兰·斯坦福青年大学托管委员会 | 2025-04-29 | — | — | CN | disclosed |
| US-20220071963-A1 | METHODS AND FORMULATIONS TO TREAT MITOCHONDRIAL DYSFUNCTION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2022-03-10 | — | — | US | disclosed |
| EP-3906027-A1 | METHODS AND FORMULATIONS TO TREAT MITOCHONDRIAL DYSFUNCTION | The Board of Trustees of the Leland Stanford Junior University (US) | 2021-11-10 | — | — | EP | disclosed |
| CN-113347972-A | Methods and formulations for treating mitochondrial dysfunction | 利兰·斯坦福青年大学托管委员会 | 2021-09-03 | — | — | CN | disclosed |
| WO-2020142547-A1 | METHODS AND FORMULATIONS TO TREAT MITOCHONDRIAL DYSFUNCTION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-07-09 | — | — | WO | disclosed |
| EP-3107901-B1 | COMPOUNDS FOR USE AS GPR120 AGONISTS | PIRAMAL ENTPR LTD (IN) | 2020-04-01 | — | — | EP | disclosed |
| US-10227360-B2 | Compounds for use as GPR120 agonists | Piramal Enterprises Limited (IN) | 2019-03-12 | — | — | US | disclosed |
| EP-3107901-A1 | COMPOUNDS FOR USE AS GPR120 AGONISTS | Piramal Enterprises Limited (IN) | 2016-12-28 | — | — | EP | disclosed |
| US-20160347768-A1 | COMPOUNDS FOR USE AS GPR120 AGONISTS | Piramal Enterprises Limited (IN) | 2016-12-01 | — | — | US | disclosed |
| WO-2015125085-A1 | COMPOUNDS FOR USE AS GPR120 AGONISTS | Piramal Enterprises Limited (IN) | 2015-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10227360-B2 | Compounds for use as GPR120 agonists | GPR119, GPR55, GPR180 | HPGD 718/4885POLB 3328/4885ALDH1A1 2823/4885 |
| US-12377077-B2 | Methods and formulations to treat mitochondrial dysfunction | AK2, PCK2, CS | HPGD 572/4885POLB 546/4885ALDH1A1 1286/4885 |
| US-20220071963-A1 | METHODS AND FORMULATIONS TO TREAT MITOCHONDRIAL DYSFUNCTION | AK2, PCK2, CS | HPGD 572/4885POLB 546/4885ALDH1A1 1286/4885 |
| US-20160347768-A1 | COMPOUNDS FOR USE AS GPR120 AGONISTS | GPR119, GPR55, GPR180 | HPGD 718/4885POLB 3328/4885ALDH1A1 2823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.