Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MC5R | P33032 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MC1R | Q01726 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289138 | 0.87 | KMT2A (0.49) | DNM1KMT2AMEN1MC5RMAPK1 | |
| SCHEMBL14531033 | 0.84 | DNM1 (0.53) | DNM1KMT2AMEN1MC5RMAPK1 | |
| SCHEMBL13430504 | 0.83 | KMT2A (0.49) | DNM1KMT2AMEN1MC5RMAPK1 | |
| SCHEMBL17240223 | 0.81 | DNM1 (0.55) | DNM1KMT2AMEN1MC5RMAPK1 | |
| SCHEMBL20824981 | 0.81 | DNM1 (0.44) | DNM1KMT2AMEN1MC5RMAPK1 | |
| SCHEMBL20824982 | 0.78 | DNM1 (0.52) | DNM1KMT2AMEN1MC5RMAPK1 | |
| SCHEMBL20495646 | 0.78 | DNM1 (0.52) | DNM1KMT2AMEN1MC5RMAPK1 | |
| SCHEMBL13995739 | 0.78 | DNM1 (0.52) | DNM1KMT2AMEN1MC5RMAPK1 | |
| SCHEMBL1703807 | 0.78 | HTR5A (0.48) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL20495653 | 0.77 | KMT2A (0.60) | DNM1KMT2AMEN1MC5RMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374034-A1 | NOVEL BICYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2023-11-23 | — | — | US | disclosed |
| US-10017522-B2 | Alpha helix mimetics and methods relating thereto | Prism BioLab Co., Ltd. (JP) | 2018-07-10 | — | — | US | disclosed |
| US-9555061-B2 | Synthesis and analysis of compounds capable of inducing differentiation of human mesenchymal stems cells into hepatocytes | National University Corporation Torrori University (JP) | 2017-01-31 | — | — | US | disclosed |
| US-20150368262-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | Prism BioLab Co., Ltd. (JP) | 2015-12-24 | — | — | US | disclosed |
| US-9040531-B2 | Alpha helix mimetics and methods relating thereto | Prism BioLab Co., Ltd. (JP) | 2015-05-26 | — | — | US | disclosed |
| US-20140112892-A1 | SYNTHESIS AND ANALYSIS OF NOVEL COMPOUND CAPABLE OF INDUCING DIFFERENTIATION OF HUMAN MESENCHYMAL STEM CELL INTO HEPATOCYTE | NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY (JP) | 2014-04-24 | — | — | US | disclosed |
| US-20120088770-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230374034-A1 | NOVEL BICYCLIC COMPOUNDS | NOTCH1, NOTCH2, HES1 | DNM1 63/4885KMT2A 2051/4885MEN1 314/4885 |
| US-20150368262-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PLOD3, COL1A1, THPO | DNM1 745/4885KMT2A 3392/4885MEN1 1064/4885 |
| US-20120088770-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PLOD3, COL1A1, THPO | DNM1 745/4885KMT2A 3392/4885MEN1 1064/4885 |
| US-20140112892-A1 | SYNTHESIS AND ANALYSIS OF NOVEL COMPOUND CAPABLE OF INDUCING DIFFERENTIATION OF HUMAN MESENCHYMAL STEM CELL INTO HEPATOCYTE | HGF, FABP1, CD14 | DNM1 2935/4885KMT2A 3564/4885MEN1 3339/4885 |
| US-10017522-B2 | Alpha helix mimetics and methods relating thereto | PLOD3, COL1A1, THPO | DNM1 745/4885KMT2A 3392/4885MEN1 1064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.