SCHEMBL1704922

SCHEMBL1704922

O=C(O)CNC1CCNCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 4/20 0.50
DPP7 Q9UHL4 1/20 0.47
POLB P06746 1/20 0.45
GABRA5 P31644 3/20 0.43
GABRB2 P47870 3/20 0.43
GABRA1 P14867 2/20 0.43
GABRA4 P48169 2/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
TSHR P16473 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA3 P34903 1/20 0.43
GABRA2 P47869 1/20 0.43
GABRE P78334 1/20 0.43
PMP22 Q01453 1/20 0.43
GABRA6 Q16445 1/20 0.43
GABRG1 Q8N1C3 1/20 0.43
GABRG3 Q99928 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL852073 0.88 KCNH2 (0.53) EPHX1DPP7POLBGABRA5GABRB2
SCHEMBL3640222 0.86 KCNH2 (0.52) EPHX1DPP7POLBGABRA5GABRB2
SCHEMBL22687353 0.84 ITGB3 (0.41) DPP7POLBDPP4FAPDPP8
SCHEMBL75440 0.84
Bicarbonate SCHEMBL10725172 0.81 ITGB3 (0.41) DPP7POLBDPP4FAPDPP8
Hydrochloric Acid SCHEMBL7602448 0.81
SCHEMBL28956884 0.81
Methane SCHEMBL27880200 0.81
SCHEMBL21911154 0.81 EPHX1 (0.48) EPHX1DPP7POLBGABRA5GABRB2
SCHEMBL12226497 0.81 EPHX1 (0.48) EPHX1DPP7POLBGABRA5GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240360177-A1 PEPTIDES WITH ANTIMICROBIAL ACTIVITIES AIMMAX THERAPEUTICS, INC. 2024-10-31 US claimed
EP-4396196-A1 PEPTIDES WITH ANTIMICROBIAL ACTIVITIES Aimmax Therapeutics, Inc. (US) 2024-07-10 EP claimed
WO-2023034481-A1 PEPTIDES WITH ANTIMICROBIAL ACTIVITIES AIMMAX THERAPEUTICS, INC. (US) 2023-03-09 WO claimed
CN-106470973-A Small molecule lfa-1 inhibitors 阿罗赛特制药公司 2017-03-01 CN claimed
US-20140112976-A1 Cyclic Peptides with an Anti-Neoplasic and Anti-Angiogenic Activity CENTRO DE INGENIERIA GENETICA BIOTECNOLOGIA (CU) 2014-04-24 US claimed
EP-2690107-A2 CYCLIC PEPTIDES WITH AN ANTI-NEOPLASIC AND ANTI-ANGIOGENIC ACTIVITY Centro De Ingenieria Genetica Y Biotecnologia (CU) 2014-01-29 EP claimed
US-20050119190-A1 Inhibitors of the blood-clotting factor xa, production thereof and use of the same CURACYTE AG (DE) 2005-06-02 US claimed
EP-1483285-A1 INHIBITORS OF THE BLOOD-CLOTTING FACTOR Xa, PRODUCTION THEREOF AND USE OF THE SAME Curacyte AG (DE) 2004-12-08 EP claimed
US-6670477-B2 Reacting 4-pyridinone with glycine NOVARTIS AG (CH) 2003-12-30 US claimed
WO-2003076457-A1 INHIBITORS OF THE BLOOD-CLOTTING FACTOR Xa, PRODUCTION THEREOF AND USE OF THE SAME CURACYTE AG (DE) 2003-09-18 WO claimed
US-20020133014-A1 Synthesis of enantiomerically enriched 4-piperidinylglycine NOVARTIS AG (CH) 2002-09-19 US claimed
US-20240360177-A1 PEPTIDES WITH ANTIMICROBIAL ACTIVITIES AIMMAX THERAPEUTICS, INC. 2024-10-31 US disclosed
US-20240327461-A1 APELIN POLYPEPTIDES AMGEN INC. (US) 2024-10-03 US disclosed
EP-4396196-A1 PEPTIDES WITH ANTIMICROBIAL ACTIVITIES Aimmax Therapeutics, Inc. (US) 2024-07-10 EP disclosed
CN-117157285-A Pharmaceutical compounds as ubiquitin-specific protease 19 (USP 19) inhibitors 阿尔麦克探索有限公司 2023-12-01 CN disclosed
WO-2000076970-A2 SERINE PROTEASE INHIBITORS ELI LILLY AND COMPANY (US) 2000-12-21 WO disclosed
WO-2000075186-A1 NEUROMEDIN B AND SOMATOSTATIN RECEPTOR AGONISTS SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES SAS (FR) 2000-12-14 WO disclosed
EP-0846125-A2 INHIBITORS OF FACTOR Xa COR THERAPEUTICS, INC. (US) 1998-06-10 EP disclosed
US-5618814-A Trisubstituted pyrimido [5,4-d] pyrimidines for modulating multi-drug resistance and pharmaceutical compositions containing these compounds DR. KARL THOMAE GMBH (DE) 1997-04-08 US disclosed
WO-1996040743-A2 INHIBITORS OF FACTOR Xa COR THERAPEUTICS, INC. (US) 1996-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020133014-A1 Synthesis of enantiomerically enriched 4-piperidinylglycine EPRS1, GRHPR, ASNS EPHX1 1342/4885DPP7 151/4885POLB 1920/4885
US-20050119190-A1 Inhibitors of the blood-clotting factor xa, production thereof and use of the same SERPINC1, TFPI, F11 EPHX1 205/4885DPP7 349/4885POLB 4086/4885
US-20240360177-A1 PEPTIDES WITH ANTIMICROBIAL ACTIVITIES VIP, FPR2, FPR1 EPHX1 3349/4885DPP7 187/4885POLB 969/4885
US-20240327461-A1 APELIN POLYPEPTIDES APLNR, FABP3, AP3B1 EPHX1 4133/4885DPP7 104/4885POLB 4706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.