Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5189137 | 0.87 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2TP53TDP1 | |
| SCHEMBL17075279 | 0.86 | KEAP1 (0.46) | SMN1; SMN2 | |
| SCHEMBL16858009 | 0.85 | TDP1 (0.42) | ALDH1A1LMNASMN1; SMN2TP53TDP1 | |
| SCHEMBL338524 | 0.85 | POLB (0.44) | ALDH1A1LMNASMN1; SMN2TP53GLA | |
| SCHEMBL17075262 | 0.82 | TAS1R3 (0.35) | ALDH1A1GLAPOLBKMT2AMAPT | |
| SCHEMBL202173 | 0.80 | TDP1 (0.50) | ALDH1A1SMN1; SMN2TDP1GLATSHR | |
| SCHEMBL14000141 | 0.79 | TSHR (0.52) | ALDH1A1GLATSHRPOLBAPOBEC3A | |
| SCHEMBL9857416 | 0.79 | TSHR (0.52) | ALDH1A1GLATSHRPOLBAPOBEC3A | |
| SCHEMBL17075287 | 0.79 | PLA2G2A (0.40) | POLB | |
| SCHEMBL547492 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2TP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10966909-B2 | Resin composites for use in dental preventive and restorative applications | ADA FOUNDATION (US) | 2021-04-06 | — | — | US | claimed |
| US-20200297587-A1 | RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ADA FOUNDATION (US) | 2020-09-24 | — | — | US | claimed |
| US-10675224-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | ADA FOUNDATION (US) | 2020-06-09 | — | — | US | claimed |
| US-20190209438-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | ADA FOUNDATION (US) | 2019-07-11 | — | — | US | claimed |
| US-10231906-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | ADA FOUNDATION (US) | 2019-03-19 | — | — | US | claimed |
| EP-3270870-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS | ADA FOUNDATION (US) | 2018-01-24 | — | — | EP | claimed |
| US-20170049666-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | ADA FOUND (US) | 2017-02-23 | — | — | US | claimed |
| US-9572753-B2 | Enzymatically and hydrolytically stable resins, resin monomers, and resin composites for use in dental preventive and restorative applications | ADA FOUNDATION (US) | 2017-02-21 | — | — | US | claimed |
| WO-2016160299-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS | ADA FOUNDATION (US) | 2016-10-06 | — | — | WO | claimed |
| US-20150257986-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ADA FOUNDATION | 2015-09-17 | — | — | US | claimed |
| US-10966909-B2 | Resin composites for use in dental preventive and restorative applications | ADA FOUNDATION (US) | 2021-04-06 | — | — | US | disclosed |
| US-20200297587-A1 | RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ADA FOUNDATION (US) | 2020-09-24 | — | — | US | disclosed |
| US-10675224-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | ADA FOUNDATION (US) | 2020-06-09 | — | — | US | disclosed |
| US-20190209438-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | ADA FOUNDATION (US) | 2019-07-11 | — | — | US | disclosed |
| US-10231906-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | ADA FOUNDATION (US) | 2019-03-19 | — | — | US | disclosed |
| EP-3270870-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS | ADA FOUNDATION (US) | 2018-01-24 | — | — | EP | disclosed |
| US-20170049666-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | ADA FOUND (US) | 2017-02-23 | — | — | US | disclosed |
| US-9572753-B2 | Enzymatically and hydrolytically stable resins, resin monomers, and resin composites for use in dental preventive and restorative applications | ADA FOUNDATION (US) | 2017-02-21 | — | — | US | disclosed |
| WO-2016160299-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS | ADA FOUNDATION (US) | 2016-10-06 | — | — | WO | disclosed |
| US-20150257986-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ADA FOUNDATION | 2015-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190209438-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | GGH, DNPH1, BCHE | ALDH1A1 321/4885LMNA 1420/4885SMN1; SMN2 2533/4885 |
| US-10675224-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | GGH, DNPH1, BCHE | ALDH1A1 321/4885LMNA 1420/4885SMN1; SMN2 2533/4885 |
| US-10966909-B2 | Resin composites for use in dental preventive and restorative applications | SUV39H2, CBX3, SUV39H1 | ALDH1A1 1332/4885LMNA 1066/4885SMN1; SMN2 3098/4885 |
| US-20170049666-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | GGH, DNPH1, BCHE | ALDH1A1 321/4885LMNA 1420/4885SMN1; SMN2 2533/4885 |
| US-20200297587-A1 | RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | SUV39H2, CBX3, SUV39H1 | ALDH1A1 1332/4885LMNA 1066/4885SMN1; SMN2 3098/4885 |
| US-20150257986-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ESD, JMJD6, DNPH1 | ALDH1A1 377/4885LMNA 1826/4885SMN1; SMN2 3272/4885 |
| US-10231906-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | GGH, DNPH1, BCHE | ALDH1A1 321/4885LMNA 1420/4885SMN1; SMN2 2533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.