Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7627812 | 0.85 | ALDH1A1 (0.42) | TAS1R3TAS1R1ALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL17075279 | 0.83 | KEAP1 (0.46) | — | |
| SCHEMBL17075258 | 0.82 | ALDH1A1 (0.41) | ALDH1A1POLBGLAMAPTKMT2A | |
| SCHEMBL13958013 | 0.74 | ESR1 (0.40) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL17075287 | 0.73 | PLA2G2A (0.40) | GAAPOLB | |
| SCHEMBL13958502 | 0.73 | NR3C1 (0.43) | ALDH1A1KDM4EGAAPOLBGLA | |
| SCHEMBL18783512 | 0.72 | TAS1R3 (0.40) | TAS1R3TAS1R1ALDH1A1KDM4EPOLB | |
| SCHEMBL5189137 | 0.70 | ALDH1A1 (0.42) | ALDH1A1GLAMAPTKMT2A | |
| SCHEMBL11647273 | 0.70 | ALDH1A1 (0.41) | TAS1R3TAS1R1ALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL7145665 | 0.70 | TAS2R14 (0.46) | ALDH1A1GAAPOLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10966909-B2 | Resin composites for use in dental preventive and restorative applications | ADA FOUNDATION (US) | 2021-04-06 | — | — | US | claimed |
| US-20200297587-A1 | RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ADA FOUNDATION (US) | 2020-09-24 | — | — | US | claimed |
| US-10675224-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | ADA FOUNDATION (US) | 2020-06-09 | — | — | US | claimed |
| US-20190209438-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | ADA FOUNDATION (US) | 2019-07-11 | — | — | US | claimed |
| US-10231906-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | ADA FOUNDATION (US) | 2019-03-19 | — | — | US | claimed |
| EP-3270870-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS | ADA FOUNDATION (US) | 2018-01-24 | — | — | EP | claimed |
| US-20170049666-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | ADA FOUND (US) | 2017-02-23 | — | — | US | claimed |
| US-9572753-B2 | Enzymatically and hydrolytically stable resins, resin monomers, and resin composites for use in dental preventive and restorative applications | ADA FOUNDATION (US) | 2017-02-21 | — | — | US | claimed |
| WO-2016160299-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS | ADA FOUNDATION (US) | 2016-10-06 | — | — | WO | claimed |
| US-20150257986-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ADA FOUNDATION | 2015-09-17 | — | — | US | claimed |
| US-10966909-B2 | Resin composites for use in dental preventive and restorative applications | ADA FOUNDATION (US) | 2021-04-06 | — | — | US | disclosed |
| US-20200297587-A1 | RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ADA FOUNDATION (US) | 2020-09-24 | — | — | US | disclosed |
| US-10675224-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | ADA FOUNDATION (US) | 2020-06-09 | — | — | US | disclosed |
| US-20190209438-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | ADA FOUNDATION (US) | 2019-07-11 | — | — | US | disclosed |
| US-10231906-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | ADA FOUNDATION (US) | 2019-03-19 | — | — | US | disclosed |
| EP-3270870-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS | ADA FOUNDATION (US) | 2018-01-24 | — | — | EP | disclosed |
| US-20170049666-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | ADA FOUND (US) | 2017-02-23 | — | — | US | disclosed |
| US-9572753-B2 | Enzymatically and hydrolytically stable resins, resin monomers, and resin composites for use in dental preventive and restorative applications | ADA FOUNDATION (US) | 2017-02-21 | — | — | US | disclosed |
| WO-2016160299-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS | ADA FOUNDATION (US) | 2016-10-06 | — | — | WO | disclosed |
| US-20150257986-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ADA FOUNDATION | 2015-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190209438-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | GGH, DNPH1, BCHE | TAS1R3 2530/4885TAS1R1 2624/4885ALDH1A1 321/4885 |
| US-10675224-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | GGH, DNPH1, BCHE | TAS1R3 2530/4885TAS1R1 2624/4885ALDH1A1 321/4885 |
| US-10966909-B2 | Resin composites for use in dental preventive and restorative applications | SUV39H2, CBX3, SUV39H1 | TAS1R3 696/4885TAS1R1 1262/4885ALDH1A1 1332/4885 |
| US-20170049666-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | GGH, DNPH1, BCHE | TAS1R3 2530/4885TAS1R1 2624/4885ALDH1A1 321/4885 |
| US-20200297587-A1 | RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | SUV39H2, CBX3, SUV39H1 | TAS1R3 696/4885TAS1R1 1262/4885ALDH1A1 1332/4885 |
| US-20150257986-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ESD, JMJD6, DNPH1 | TAS1R3 1984/4885TAS1R1 2043/4885ALDH1A1 377/4885 |
| US-10231906-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | GGH, DNPH1, BCHE | TAS1R3 2530/4885TAS1R1 2624/4885ALDH1A1 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.