Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21980744 | 0.88 | MEN1 (0.36) | — | |
| SCHEMBL11801014 | 0.86 | CA12 (0.30) | — | |
| SCHEMBL126719 | 0.84 | CA7 (0.48) | — | |
| Potassium Ion SCHEMBL6555501 | 0.80 | — | — | |
| Zinc Ion SCHEMBL7097317 | 0.78 | CA7 (0.42) | — | |
| SCHEMBL29678173 | 0.78 | CA7 (0.42) | — | |
| Potassium Ion SCHEMBL11696318 | 0.78 | CA7 (0.42) | — | |
| Potassium Ion SCHEMBL8994748 | 0.74 | MEN1 (0.33) | — | |
| SCHEMBL5489 | 0.62 | — | — | |
| Sulfuric Acid SCHEMBL7334619 | 0.61 | ALDH1A1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719391-A2 | TRIPLE KINASE INHIBITORS | Unogen Biotech Ltd. (US) | 2026-04-08 | — | — | EP | disclosed |
| US-20260085050-A1 | TRIPLE KINASE INHIBITORS | UNOGEN BIOTECH LTD (US) | 2026-03-26 | — | — | US | disclosed |
| WO-2025137307-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| CN-119899172-A | KIF18A inhibitor and application thereof | 轩竹生物科技股份有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-119562952-A | KIF18A inhibitors | 山东轩竹医药科技有限公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2024249831-A2 | TRIPLE KINASE INHIBITORS | UNOGEN BIOTECH LTD. (US) | 2024-12-05 | — | — | WO | disclosed |
| WO-2024240062-A1 | PYRIDINE-PYRROLO DERIVATIVE AND USE THEREOF IN DRUGS | 广东东阳光药业股份有限公司 | 2024-11-28 | — | — | WO | disclosed |
| CN-117881661-A | Condensed heterocyclic derivative | 杨森科学爱尔兰无限公司 | 2024-04-12 | — | — | CN | disclosed |
| WO-2024067465-A1 | KIF18A INHIBITOR | 山东轩竹医药科技有限公司 | 2024-04-04 | — | — | WO | disclosed |
| CN-117069684-A | Method for synthesizing sulfur-containing alkenyl halogenated benzopyran derivative | 温州大学 | 2023-11-17 | — | — | CN | disclosed |
| US-9598415-B2 | Compounds as modulators of RORγ | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-03-21 | — | — | US | disclosed |
| EP-3131902-A1 | COMPOUNDS AS MODULATORS OF ROR GAMMA | Boehringer Ingelheim International GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |
| US-20170008894-A1 | COMPOUNDS AS MODULATORS OF ROR GAMMA | BOEHRINGER INGELHEIM INT (DE) | 2017-01-12 | — | — | US | disclosed |
| CN-103596921-B | Chiral synthesis of N- {3, 4-difluoro-2- [ (2-fluoro-4-iodophenyl) amino ] -6-methoxyphenyl } -1- (2, 3-dihydroxypropyl) cyclopropylsulfonamide | 拜耳知识产权有限责任公司 | 2016-08-03 | — | — | CN | disclosed |
| US-20160075706-A1 | COMPOUNDS AS MODULATORS OF ROR GAMMA | BOEHRINGER INGELHEIM INT (DE) | 2016-03-17 | — | — | US | disclosed |
| WO-2016035008-A1 | PYRIDOPYRIMIDINE DERIVATIVES AS MEK INHIBITORS | LUPIN LIMITED (IN) | 2016-03-10 | — | — | WO | disclosed |
| US-9242989-B2 | Compounds as modulators of RORγ | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-01-26 | — | — | US | disclosed |
| WO-2015160654-A1 | COMPOUNDS AS MODULATORS OF ROR GAMMA | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-10-22 | — | — | WO | disclosed |
| US-20150291607-A1 | COMPOUNDS AS MODULATORS OF ROR GAMMA | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-10-15 | — | — | US | disclosed |
| CN-103596921-A | Chiral synthesis of N- {3, 4-difluoro-2- [ (2-fluoro-4-iodophenyl) amino ] -6-methoxyphenyl } -1- (2, 3-dihydroxypropyl) cyclopropylsulfonamide | BAYER IP GMBH | 2014-02-19 | — | — | CN | disclosed |