SCHEMBL1720049

SCHEMBL1720049

CCCCCCCCCCCCCC(=O)C[N+](C)(C)C(=O)CCCCCCCCCCCCC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
MAPT P10636 1/20 0.50
CES2 O00748 3/20 0.46
CES1 P23141 3/20 0.46
HAO1 Q9UJM8 1/20 0.46
GPR84 Q9NQS5 7/20 0.45
PPARG P37231 6/20 0.45
PPARD Q03181 6/20 0.45
PPARA Q07869 6/20 0.45
HDAC11 Q96DB2 5/20 0.45
TSHR P16473 4/20 0.45
ALDH1A1 P00352 2/20 0.45
TLR2 O60603 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
FABP4 P15090 2/20 0.45
PTPN1 P18031 2/20 0.45
SLC22A6 Q4U2R8 1/20 0.45
SLC22A8 Q8TCC7 1/20 0.45
MEN1 O00255 1/20 0.45
ESR1 P03372 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16061965 1.00 KMT2A (0.50) KMT2AMAPTCES2CES1HAO1
Propane SCHEMBL322960 0.98 KMT2A (0.48) KMT2AMAPTCES2CES1HAO1
Propane SCHEMBL743689 0.98 KMT2A (0.48) KMT2AMAPTCES2CES1HAO1
Hydrochloric Acid SCHEMBL27720432 0.98 KMT2A (0.48) KMT2AMAPTCES2CES1HAO1
Propane SCHEMBL29226175 0.98 KMT2A (0.48) KMT2AMAPTCES2CES1HAO1
SCHEMBL2905137 0.90 FAAH (0.58) KMT2AMAPTPPARGPPARDPPARA
Propane SCHEMBL28144123 0.88 FAAH (0.57) KMT2AMAPTPPARGPPARDPPARA
Propane SCHEMBL741627 0.88 FAAH (0.57) KMT2AMAPTPPARGPPARDPPARA
Propane SCHEMBL26102539 0.87 FAAH (0.55) KMT2AMAPTPPARGPPARDPPARA
Phosphoric Acid SCHEMBL1223979 0.84 FABP3 (0.54) KMT2AMAPTPPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4294450-B1 METHODS FOR PREPARATION OF PLASMID DNA/LIPID PARTICLES WITH DEFINED SIZE FOR IN VITRO AND IN VIVO TRANSFECTION UNIV JOHNS HOPKINS (US) 2026-02-04 EP claimed
US-20240115513-A1 METHODS FOR PREPARATION OF PLASMID DNA/LIPID PARTICLES WITH DEFINED SIZE FOR IN VITRO AND IN VIVO TRANSFECTION THE JOHNS HOPKINS UNIVERSITY 2024-04-11 US claimed
EP-4294450-A1 METHODS FOR PREPARATION OF PLASMID DNA/LIPID PARTICLES WITH DEFINED SIZE FOR IN VITRO AND IN VIVO TRANSFECTION The Johns Hopkins University (US) 2023-12-27 EP claimed
WO-2022177977-A1 METHODS FOR PREPARATION OF PLASMID DNA/LIPID PARTICLES WITH DEFINED SIZE FOR IN VITRO AND IN VIVO TRANSFECTION THE JOHNS HOPKINS UNIVERSITY (US) 2022-08-25 WO claimed
EP-2925303-A1 PROSTACYLIN COMPOSITIONS AND METHODS FOR USING THE SAME Insmed Incorporated (US) 2015-10-07 EP claimed
WO-2014085813-A1 PROSTACYLIN COMPOSITIONS AND METHODS FOR USING THE SAME INSMED INCORPORATED (US) 2014-06-05 WO claimed
US-12616678-B2 Methods to of aldehyde dehydrogenases for treatment of cancer THE PENN STATE RESEARCH FOUNDATION (PA) 2026-05-05 US disclosed
US-20260060944-A1 PHARMACEUTICAL COMPOSITION AND USE THEREOF SHIH KUEI CHUNG (TW) 2026-03-05 US disclosed
US-12551434-B2 Zwitterionic polymer particle compositions and related methods WAYNE STATE UNIVERSITY (US) 2026-02-17 US disclosed
EP-4294450-B1 METHODS FOR PREPARATION OF PLASMID DNA/LIPID PARTICLES WITH DEFINED SIZE FOR IN VITRO AND IN VIVO TRANSFECTION UNIV JOHNS HOPKINS (US) 2026-02-04 EP disclosed
US-20250387367-A1 METHODS AND COMPOSITIONS RELATING TO INHIBITION OF ALDEHYDE DEHYDROGENASES FOR TREATMENT OF CANCER PENN STATE RES FOUND (US) 2025-12-25 US disclosed
US-20250312430-A1 COMPOSITIONS OF LIPID NANOPARTICLES FOR PLASMID DNA DELIVERY TO THE LIVER AND METHODS FOR PREPARING THE SAME THE JOHNS HOPKINS UNIVERSITY 2025-10-09 US disclosed
EP-4499045-A1 COMPOSITIONS OF LIPID NANOPARTICLES FOR PLASMID DNA DELIVERY TO THE LIVER AND METHODS FOR PREPARING THE SAME The Johns Hopkins University (US) 2025-02-05 EP disclosed
EP-1001750-B1 STABLE PARTICULATE COMPLEXES WITH NEUTRAL OR NEGATIVE GLOBALE CHARGE OF LAMELLAR STRUCTURE CEVA SANTE ANIMALE (FR) 2004-09-22 EP disclosed
EP-1404298-A2 A METHOD FOR PREPARATION OF VESICLES LOADED WITH BIOLOGICAL MATERIAL AND DIFFERENT USES THEREOF YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2004-04-07 EP disclosed
WO-2003000227-A2 A METHOD FOR PREPARATION OF VESICLES LOADED WITH BIOLOGICAL MATERIAL AND DIFFERENT USES THEREOF YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2003-01-03 WO disclosed
US-6096335-A COMPLEX CONTAINING LIPID BIOVECTOR THERAPEUTICS, S.A. (FR) 2000-08-01 US disclosed
EP-1001750-A1 STABLE PARTICULATE COMPLEXES WITH NEUTRAL OR NEGATIVE GLOBALE CHARGE OF LAMELLAR STRUCTURE Biovector Therapeutics S.A. (FR) 2000-05-24 EP disclosed
WO-1999006026-A9 STABLE PARTICULATE COMPLEXES WITH NEUTRAL OR NEGATIVE GLOBAL CHARGE OF LAMELLAR STRUCTURE BIOVECTOR THERAPEUTICS SA (FR) 1999-04-29 WO disclosed
WO-1999006026-A1 STABLE PARTICULATE COMPLEXES WITH NEUTRAL OR NEGATIVE GLOBAL CHARGE OF LAMELLAR STRUCTURE BIOVECTOR THERAPEUTICS (S.A.) (FR) 1999-02-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060944-A1 PHARMACEUTICAL COMPOSITION AND USE THEREOF LETM1, MCU, TFAM KMT2A 2146/4885MAPT 3451/4885CES2 3531/4885
US-20250387367-A1 METHODS AND COMPOSITIONS RELATING TO INHIBITION OF ALDEHYDE DEHYDROGENASES FOR TREATMENT OF CANCER ALDH3A1, ALDH2, ADH1C KMT2A 2357/4885MAPT 4736/4885CES2 96/4885
US-20250312430-A1 COMPOSITIONS OF LIPID NANOPARTICLES FOR PLASMID DNA DELIVERY TO THE LIVER AND METHODS FOR PREPARING THE SAME STAT6, CD4, NFATC1 KMT2A 2112/4885MAPT 3597/4885CES2 3078/4885
US-12616678-B2 Methods to of aldehyde dehydrogenases for treatment of cancer ALDH1A1, ALDH3A1, ADH1C KMT2A 777/4885MAPT 4198/4885CES2 124/4885
US-12551434-B2 Zwitterionic polymer particle compositions and related methods IAPP, GIPR, INSR KMT2A 3391/4885MAPT 1706/4885CES2 4253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.