Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.95 |
| ▸ | ESR1 | P03372 | 2/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.63 |
| ▸ | TACR2 | P21452 | 2/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | SHBG | P04278 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.63 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | TST | Q16762 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11737365 | 1.00 | PTGS2 (1.00) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| Cardol SCHEMBL406402 | 1.00 | PTGS2 (1.00) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL2464812 | 1.00 | PTGS2 (1.00) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL4448056 | 1.00 | PTGS2 (1.00) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL16432840 | 1.00 | PTGS2 (1.00) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL1914183 | 1.00 | PTGS2 (1.00) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL16431835 | 1.00 | PTGS2 (1.00) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL2468227 | 1.00 | PTGS2 (1.00) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL2178058 | 1.00 | PTGS2 (1.00) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL70057 | 1.00 | PTGS2 (1.00) | PTGS2CYP3A4ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250090554-A1 | A METHOD OF TREATING DEPRESSION BY IMMUNE MODULATION | MYND LIFE SCIENCES INC (CA) | 2025-03-20 | — | — | US | disclosed |
| US-20220323372-A1 | COMPOSITION FOR IMPROVING LIVER FUNCTION | NITTO FUJI FLOUR MILLING CO., LTD. (JP) | 2022-10-13 | — | — | US | disclosed |
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| EP-3974026-A1 | COMPOSITION FOR IMPROVING LIVER FUNCTION | Nitto Fuji Flour Milling Co., Ltd. (JP) | 2022-03-30 | — | — | EP | disclosed |
| WO-2020235546-A1 | COMPOSITION FOR IMPROVING LIVER FUNCTION | 日東富士製粉株式会社 (JP) | 2020-11-26 | — | — | WO | disclosed |
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-9737494-B2 | Method of regulating circadian rhythm, and method of preparing circadian rhythm regulatory agent | NAT'L INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 2017-08-22 | — | — | US | disclosed |
| US-20170095428-A1 | AGENT FOR IMPROVING GLUCOSE TOLERANCE DISORDER | NISSHIN SEIFUN GROUP (JP) | 2017-04-06 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |
| US-20150306045-A1 | METHOD OF REGULATING CIRCADIAN RHYTHM, AND METHOD OF PREPARING CIRCADIAN RHYTHM REGULATORY AGENT | NAT'L INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170095428-A1 | AGENT FOR IMPROVING GLUCOSE TOLERANCE DISORDER | GPR119, SLC2A3, SLC2A1 | PTGS2 2926/4885CYP3A4 2916/4885ESR1 3384/4885 |
| US-20220323372-A1 | COMPOSITION FOR IMPROVING LIVER FUNCTION | LIPC, OAT, GYS2 | PTGS2 2997/4885CYP3A4 218/4885ESR1 4040/4885 |
| US-20150306045-A1 | METHOD OF REGULATING CIRCADIAN RHYTHM, AND METHOD OF PREPARING CIRCADIAN RHYTHM REGULATORY AGENT | CRY1, PER2, ARNT | PTGS2 1899/4885CYP3A4 262/4885ESR1 2060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.