Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 13/20 | 0.48 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20000560 | 0.86 | ELOVL1 (0.61) | ACACBELOVL1HRH4 | |
| SCHEMBL799028 | 0.77 | ACACB (0.46) | ACACBELOVL1HRH4 | |
| SCHEMBL7337356 | 0.73 | LTA4H (0.52) | — | |
| SCHEMBL15019849 | 0.73 | LTA4H (0.52) | — | |
| SCHEMBL5729251 | 0.73 | LDHA (0.40) | HRH4 | |
| SCHEMBL19468728 | 0.72 | ELOVL1 (0.58) | ACACBELOVL1HRH4 | |
| SCHEMBL19468798 | 0.72 | ELOVL1 (0.55) | ACACBELOVL1HRH4 | |
| SCHEMBL5731145 | 0.70 | LMNA (0.38) | HRH4 | |
| SCHEMBL2270031 | 0.70 | HTR7 (0.44) | HRH4 | |
| SCHEMBL5728966 | 0.70 | LNPEP (0.41) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071475-A1 | UREA DERIVATIVES HAVING PI3K-INHIBITING ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2012-03-22 | — | — | US | disclosed |
| EP-2426135-A1 | UREA DERIVATIVE HAVING PI3K INHIBITORY ACTIVITY | Shionogi&Co., Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071475-A1 | UREA DERIVATIVES HAVING PI3K-INHIBITING ACTIVITY | MTOR, STAT3, SLC14A1 | ACACB 2037/4885ELOVL1 3356/4885HRH4 3729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.