Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745620 | 0.86 | ALDH1A1 (0.44) | RAPGEF4ALDH1A1L3MBTL1PDK2KDM4E | |
| SCHEMBL9743119 | 0.81 | TRPA1 (0.50) | RAPGEF4ALDH1A1L3MBTL1PDK2CA1 | |
| SCHEMBL28600277 | 0.80 | ALDH1A1 (0.46) | RAPGEF4ALDH1A1L3MBTL1PDK2MAPT | |
| SCHEMBL13044877 | 0.79 | GABRA1 (0.41) | ALDH1A1CA1CA2KDM4EMAPT | |
| SCHEMBL27404519 | 0.78 | RAPGEF4 (0.40) | RAPGEF4ALDH1A1PDK2KDM4EMAPT | |
| SCHEMBL22855607 | 0.78 | HKDC1 (0.36) | RAPGEF4ALDH1A1L3MBTL1PDK2KDM4E | |
| SCHEMBL30485469 | 0.78 | HKDC1 (0.36) | RAPGEF4ALDH1A1L3MBTL1PDK2KDM4E | |
| SCHEMBL11323890 | 0.75 | CA1 (0.45) | ALDH1A1PDK2CA1CA2CA7 | |
| SCHEMBL30578879 | 0.74 | ALOX5 (0.41) | ALDH1A1L3MBTL1PDK2MAPTELANE | |
| SCHEMBL11785835 | 0.72 | PDK2 (0.45) | ALDH1A1L3MBTL1PDK2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143006-B1 | SYNTHESIS OF ARYL COUPLED BIS PHENOXIDES AND THEIR USE IN OLEFIN POLYMERIZATION CATALYST SYSTEMS WITH ACTIVATOR-SUPPORTS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2018-07-25 | — | — | EP | disclosed |
| US-9663594-B2 | Synthesis of aryl coupled bis phenoxides and their use in olefin polymerization catalyst systems with activator-supports | CHEVRON PHILIPS CHEMICAL COMPANY LP (US) | 2017-05-30 | — | — | US | disclosed |
| US-9663594-B2 | Synthesis of aryl coupled bis phenoxides and their use in olefin polymerization catalyst systems with activator-supports | CHEVRON PHILIPS CHEMICAL COMPANY LP (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160289351-A1 | Synthesis of Aryl Coupled BIS Phenoxides and Their Use in Olefin Polymerization Catalyst Systems With Activator-Supports | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2016-10-06 | — | — | US | disclosed |
| US-20160289351-A1 | Synthesis of Aryl Coupled BIS Phenoxides and Their Use in Olefin Polymerization Catalyst Systems With Activator-Supports | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2016-10-06 | — | — | US | disclosed |
| US-9394387-B2 | Synthesis of aryl coupled bis phenoxides and their use in olefin polymerization catalyst systems with activator-supports | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2016-07-19 | — | — | US | disclosed |
| US-9394387-B2 | Synthesis of aryl coupled bis phenoxides and their use in olefin polymerization catalyst systems with activator-supports | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2016-07-19 | — | — | US | disclosed |
| US-20150329652-A1 | Synthesis of Aryl Coupled BIS Phenoxides and Their Use in Olefin Polymerization Catalyst Systems With Activator-Supports | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2015-11-19 | — | — | US | disclosed |
| US-20150329652-A1 | Synthesis of Aryl Coupled BIS Phenoxides and Their Use in Olefin Polymerization Catalyst Systems With Activator-Supports | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2015-11-19 | — | — | US | disclosed |
| WO-2015175636-A1 | SYNTHESIS OF ARYL COUPLED BIS PHENOXIDES AND THEIR USE IN OLEFIN POLYMERIZATION CATALYST SYSTEMS WITH ACTIVATOR-SUPPORTS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2015-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329652-A1 | Synthesis of Aryl Coupled BIS Phenoxides and Their Use in Olefin Polymerization Catalyst Systems With Activator-Supports | PPOX, AOC2, AOC3 | RAPGEF4 446/4885ALDH1A1 1691/4885L3MBTL1 4380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.