SCHEMBL17278608

SCHEMBL17278608

CC1(C)c2ccccc2N(c2ccc(-c3cccc(-c4ccccc4)n3)cc2)c2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.47
▸ MEN1 O00255 2/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ PDE6D O43924 1/20 0.38
▸ ASIC3 Q9UHC3 1/20 0.38
▸ RARA P10276 1/20 0.36
▸ RARB P10826 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ MAPT P10636 2/20 0.36
▸ POLB P06746 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ ADAMTS5 Q9UNA0 1/20 0.35
▸ EGLN1 Q9GZT9 3/20 0.35
▸ PGR P06401 1/20 0.34
▸ CYP1A2 P05177 2/20 0.33
▸ CYP2D6 P10635 2/20 0.33
▸ FAAH O00519 1/20 0.33
▸ MGLL Q99685 1/20 0.33
▸ RARG P13631 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17278550 0.92 KMT2A (0.40) KMT2AMEN1RAB9APDE6DASIC3
SCHEMBL17830132 0.89 KMT2A (0.41) KMT2AMEN1PDE6DALDH1A1MAPT
SCHEMBL17278610 0.89 KMT2A (0.44) KMT2AMEN1RAB9AASIC3RARA
SCHEMBL18383121 0.89 KMT2A (0.41) KMT2AMEN1PDE6DALDH1A1MAPT
SCHEMBL13231629 0.89 RARA (0.38) KMT2AMEN1RAB9ARARARARB
SCHEMBL22969712 0.88 MEN1 (0.39) KMT2AMEN1RAB9APDE6DRARA
SCHEMBL13827557 0.86 FAAH (0.44) KMT2AMEN1RAB9APDE6DALDH1A1
SCHEMBL21291481 0.86 MEN1 (0.46) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL12939257 0.86 MEN1 (0.46) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL17278600 0.86 MEN1 (0.46) KMT2AMEN1ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-04-11 — — US disclosed
US-10186665-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-01-22 — — US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 — — US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 — — US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 — — US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 — — US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 — — US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 — — US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 — — US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT TCF4, TRPA1, EML4 KMT2A 1347/4885MEN1 2279/4885RAB9A 1741/4885
US-11730052-B2 Light-emitting device GRK7, GRK1, CTNND1 KMT2A 3535/4885MEN1 3144/4885RAB9A 808/4885
US-10186665-B2 Organic electroluminescent element TCF4, TRPA1, EML4 KMT2A 1347/4885MEN1 2279/4885RAB9A 1741/4885
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AOC2, AZI2, RER1 KMT2A 1282/4885MEN1 886/4885RAB9A 2437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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