Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS known ✓ | P14324 | 1/20 | 0.39 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.39 |
| ▸ | THRA known ✓ | P10827 | 1/20 | 0.37 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625084 | 1.00 | S1PR2 (0.46) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL30343169 | 1.00 | S1PR2 (0.46) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL713063 | 1.00 | S1PR2 (0.46) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL6402056 | 0.98 | S1PR2 (0.43) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL8388882 | 0.90 | EPHX2 (0.52) | S1PR2S1PR1S1PR3S1PR5EPHX2 | |
| SCHEMBL82226 | 0.90 | EPHX2 (0.52) | S1PR2S1PR1S1PR3S1PR5EPHX2 | |
| Potassium Ion SCHEMBL1820922 | 0.87 | EPHX2 (0.49) | EPHX2FAAH | |
| Taurine SCHEMBL31682421 | 0.86 | LMNA (0.40) | S1PR2S1PR1S1PR3S1PR5RECQL | |
| Taurine SCHEMBL30343181 | 0.83 | S1PR2 (0.40) | S1PR2S1PR1S1PR3S1PR5RECQL | |
| SCHEMBL2925349 | 0.78 | S1PR2 (0.52) | S1PR2S1PR1S1PR3S1PR5DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867664-B1 | COSMETIC FOR EYELASH | KAO CORP (JP) | 2011-11-30 | — | — | EP | claimed |
| JP-2090936-A | — | — | None | — | — | JP | disclosed |
| CN-113811283-B | Liquid oil-in-water composition | 株式会社高丝 | 2025-01-28 | — | — | CN | disclosed |
| CN-115243666-A | Ceramide proliferation promoter | 高砂香料工业株式会社 | 2022-10-25 | — | — | CN | disclosed |
| JP-H0290936-A | OIL-IN-WATER TYPE EMULSION COMPOSITION | KOBAYASHI KOSE CO LTD | 1990-03-30 | — | — | JP | disclosed |