SCHEMBL17309739

SCHEMBL17309739

CCSc1cccnc1-c1nc2cc(C(F)(F)F)cc(C#N)c2n1C

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 1/20 0.36
▸ EIF4EBP1 Q13541 14/20 0.35
▸ PKM P14618 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ CLK1 P49759 1/20 0.32
▸ MAPK14 Q16539 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29431576 1.00 AR (0.36) AREIF4EBP1PKMKDM4EALDH1A1
SCHEMBL14677802 0.85 DDR1 (0.35) MAPK14
SCHEMBL17309730 0.85 MAPK14 (0.33) EIF4EBP1MAPK14
SCHEMBL15929938 0.82 PTGS2 (0.35) EIF4EBP1
SCHEMBL29431654 0.82 PTGS2 (0.35) EIF4EBP1
SCHEMBL14677508 0.80 HTR2B (0.39) KDM4EMAPK14
SCHEMBL29431603 0.79 POLB (0.48) PKMKDM4EALDH1A1LMNAHPGD
SCHEMBL14676724 0.79 POLB (0.48) PKMKDM4EALDH1A1LMNAHPGD
SCHEMBL15868310 0.75 NPC1 (0.35) KDM4ELMNA
SCHEMBL14677382 0.74 NPC1 (0.35) KDM4EALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112021322-B Compositions and methods for controlling pests 住友化学株式会社 2022-04-01 — — CN disclosed
CN-112021322-A Compositions and methods for controlling pests 住友化学株式会社 2020-12-04 — — CN disclosed
EP-2952099-B1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2018-10-17 — — EP disclosed
EP-2952097-B1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2018-10-10 — — EP disclosed
EP-2952100-B1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2018-10-10 — — EP disclosed
US-9974307-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-22 — — US disclosed
US-9883675-B2 Method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-06 — — US disclosed
US-9854805-B2 Composition and method for controlling pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-02 — — US disclosed
EP-2952098-B1 PEST-CONTROL METHOD SUMITOMO CHEMICAL CO (JP) 2017-12-20 — — EP disclosed
US-9723835-B2 Pest control composition and method for controlling pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-08 — — US disclosed
EP-2962565-A1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2016-01-06 — — EP disclosed
US-20150366207-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-24 — — US disclosed
US-20150366208-A1 METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-24 — — US disclosed
US-20150359223-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-17 — — US disclosed
US-20150359222-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-17 — — US disclosed
US-20150359219-A1 PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-17 — — US disclosed
EP-2952097-A1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2015-12-09 — — EP disclosed
EP-2952100-A1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2015-12-09 — — EP disclosed
EP-2952099-A1 PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2015-12-09 — — EP disclosed
EP-2952098-A1 PEST-CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2015-12-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150366207-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS NIT2, CRY1, CNPY2 AR 3156/4885EIF4EBP1 2918/4885PKM 3409/4885
US-20150359222-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS TH, TCOF1, BLVRB AR 4140/4885EIF4EBP1 399/4885PKM 2637/4885
US-20150359223-A1 COMPOSITION AND METHOD FOR CONTROLLING PESTS PNPO, NAMPT, NNT AR 2709/4885EIF4EBP1 2518/4885PKM 859/4885
US-20150359219-A1 PEST CONTROL COMPOSITION AND METHOD FOR CONTROLLING PEST ABAT, PNPO, GABBR1 AR 4632/4885EIF4EBP1 693/4885PKM 1655/4885
US-20150366208-A1 METHOD FOR CONTROLLING PESTS BROX, RNGTT, NOS1 AR 4718/4885EIF4EBP1 3030/4885PKM 4320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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