Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13834151 | 0.86 | NPC1 (0.42) | ACHELMNAMTNR1AMAPTALDH1A1 | |
| SCHEMBL29173698 | 0.74 | ALOX15 (0.42) | KDM4EHSD17B10KMT2ALMNAGAA | |
| SCHEMBL28684424 | 0.73 | RAB9A (0.42) | KDM4EHSD17B10KMT2ALMNAGAA | |
| SCHEMBL17320137 | 0.71 | BAZ2B (0.42) | KDM4EKMT2ALMNAGAAHPGD | |
| SCHEMBL15558301 | 0.71 | ALOX15 (0.60) | ACHEKDM4EHSD17B10KMT2ALMNA | |
| SCHEMBL2470098 | 0.70 | LMNA (0.40) | KDM4EHSD17B10LMNAGAAHPGD | |
| SCHEMBL22415249 | 0.70 | MTNR1A (0.36) | KDM4EHSD17B10GAAHPGDMTNR1A | |
| SCHEMBL29507033 | 0.70 | LMNA (0.40) | KDM4EHSD17B10LMNAGAAHPGD | |
| SCHEMBL8959923 | 0.70 | KDM4E (0.37) | KDM4EHSD17B10GAAHPGDMTNR1A | |
| SCHEMBL2476989 | 0.70 | ABCB11 (0.46) | KDM4EHSD17B10KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531488-B1 | INDIRUBIN-3'-OXIME DERIVATIVES AS POTENT CYCLIN DEPENDENT KINASE INHIBITORS | ANYGEN CO LTD (KR) | 2015-12-09 | — | — | EP | disclosed |