SCHEMBL17320738

SCHEMBL17320738

c1cc(-c2ccc3ccccc3c2)cc(-c2c3ccccc3c(-c3ccc(-c4cccc5oc6ccccc6c45)cc3)c3ccccc23)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B1 P14061 1/20 0.39
▸ HSD17B2 P37059 1/20 0.39
▸ PLA2G2A P14555 2/20 0.38
▸ PLA2G4A P47712 2/20 0.38
▸ CASP3 P42574 1/20 0.36
▸ SENP7 Q9BQF6 1/20 0.36
▸ SENP6 Q9GZR1 1/20 0.36
▸ HCRTR1 O43613 1/20 0.36
▸ PLA2G10 O15496 1/20 0.36
▸ BACE1 P56817 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ HDAC4 P56524 1/20 0.35
▸ HDAC2 Q92769 1/20 0.35
▸ HDAC8 Q9BY41 1/20 0.35
▸ GPR84 Q9NQS5 1/20 0.35
▸ ALOX5 P09917 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ PRKDC P78527 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17320839 0.97 PLA2G2A (0.41) HSD17B1HSD17B2PLA2G2APLA2G4ACASP3
SCHEMBL17320741 0.96 L3MBTL1 (0.38) HSD17B1HSD17B2CASP3SENP7SENP6
SCHEMBL27341401 0.95 HSD17B1 (0.37) HSD17B1HSD17B2PLA2G2APLA2G4ACASP3
SCHEMBL22063390 0.95 HDAC4 (0.40) HSD17B1HSD17B2PLA2G2APLA2G4ACASP3
SCHEMBL24090052 0.95 ESR1 (0.39) HSD17B1HSD17B2PLA2G2APLA2G4ACASP3
SCHEMBL22063079 0.93 HSD17B1 (0.40) HSD17B1HSD17B2PLA2G2APLA2G4ACASP3
SCHEMBL26404382 0.92 PLA2G2A (0.42) HSD17B1HSD17B2PLA2G2APLA2G4ACASP3
SCHEMBL26949957 0.92 HSD17B1 (0.39) HSD17B1HSD17B2PLA2G2APLA2G4ACASP3
SCHEMBL22062620 0.92 HDAC4 (0.42) HSD17B1HSD17B2CASP3SENP7SENP6
SCHEMBL27341266 0.91 L3MBTL1 (0.37) HSD17B1HSD17B2BACE1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11665962-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-05-30 — — US disclosed
US-11665962-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-05-30 — — US disclosed
US-20210384445-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2021-12-09 — — US disclosed
US-20210320251-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-14 — — US disclosed
US-20200212315-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, AND COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2020-07-02 — — US disclosed
US-20200185620-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-06-11 — — US disclosed
US-20200181160-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-06-11 — — US disclosed
US-10347842-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-09 — — US disclosed
US-20180138417-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2018-05-17 — — US disclosed
US-20180138417-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2018-05-17 — — US disclosed
US-9893289-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-13 — — US disclosed
US-9893289-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-13 — — US disclosed
US-20160211458-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-21 — — US disclosed
US-20160211458-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-21 — — US disclosed
US-20160020405-A1 ORGANIC LIGHT EMITTING ELEMENT AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-21 — — US disclosed
US-20160020405-A1 ORGANIC LIGHT EMITTING ELEMENT AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-21 — — US disclosed
US-20150357574-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-10 — — US disclosed
US-20150357574-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210320251-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE OLA1, TAS2R19, TMEM109 HSD17B1 4559/4885HSD17B2 4273/4885PLA2G2A 2077/4885
US-20200212315-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, AND COMPOUND OR10J3, ESR1, NFE2L2 HSD17B1 944/4885HSD17B2 742/4885PLA2G2A 1906/4885
US-20200181160-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE AHR, EMC2, NFE2L2 HSD17B1 1288/4885HSD17B2 362/4885PLA2G2A 4761/4885
US-20210384445-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE ESR1, EML4, L1CAM HSD17B1 950/4885HSD17B2 623/4885PLA2G2A 4198/4885
US-20200185620-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE EMC2, NFE2L2, AOC2 HSD17B1 2137/4885HSD17B2 724/4885PLA2G2A 4685/4885
US-11665962-B2 Organic electroluminescence element and electronic device ESR1, EML4, L1CAM HSD17B1 950/4885HSD17B2 623/4885PLA2G2A 4198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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