SCHEMBL17345014

SCHEMBL17345014

C=CC(=O)NCCOCCOC(=O)C(=C)C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.54
TSHR P16473 6/20 0.43
ALDH1A1 P00352 5/20 0.43
TP53 P04637 2/20 0.43
HIF1A Q16665 2/20 0.43
HSD17B10 Q99714 1/20 0.43
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
MAPK1 P28482 1/20 0.38
TGM2 P21980 2/20 0.34
GAA P10253 1/20 0.34
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PYGL P06737 1/20 0.32
CA1 P00915 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17522070 1.00 THRB (0.54) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL14165100 0.97 THRB (0.54) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL3818410 0.92 THRB (0.46) THRBTSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL24036478 0.86 TGM2 (0.42) THRBTSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL22035556 0.86 THRB (0.45) THRBTSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL21496227 0.86 TSHR (0.47) THRBTSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL17345313 0.85 TSHR (0.50) THRBTSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL11337160 0.85 TSHR (0.57) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL12328384 0.84 TSHR (0.52) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL12213321 0.84 TSHR (0.52) THRBTSHRALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230270630-A1 COMPOSITION FOR DENTAL ATTACHMENT KURARAY NORITAKE DENTAL INC. (JP) 2023-08-31 US claimed
EP-4193985-A1 COMPOSITION FOR DENTAL ATTACHMENT Kuraray Noritake Dental Inc. (JP) 2023-06-14 EP claimed
CN-116096339-A Dental attachment composition 可乐丽则武齿科株式会社 2023-05-09 CN claimed
WO-2022030642-A1 COMPOSITION FOR DENTAL ATTACHMENT クラレノリタケデンタル株式会社 2022-02-10 WO claimed
CN-108289794-B Dental adhesive 可乐丽则武齿科株式会社 2021-10-01 CN claimed
EP-3388046-B1 DENTAL ADHESIVE KURARAY NORITAKE DENTAL INC (JP) 2020-06-10 EP claimed
US-10456333-B2 Dental adhesive KURARAY NORITAKE DENTAL INC. (JP) 2019-10-29 US claimed
US-20180360696-A1 DENTAL ADHESIVE KURARAY NORITAKE DENTAL INC. (JP) 2018-12-20 US claimed
EP-3388046-A1 DENTAL ADHESIVE Kuraray Noritake Dental Inc. (JP) 2018-10-17 EP claimed
US-9844495-B2 Self-adhesive dental composite resin KURARAY NORITAKE DENTAL INC. (JP) 2017-12-19 US claimed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
EP-4736834-A1 DENTAL COMPOSITION KIT Kuraray Noritake Dental Inc. (JP) 2026-05-06 EP disclosed
US-20260053717-A1 CARIOUS TOOTH STRUCTURE RECOVERY AGENT, AND DENTAL ADHESIVE KIT KURARAY NORITAKE DENTAL INC. (JP) 2026-02-26 US disclosed
EP-4659730-A1 DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-12-10 EP disclosed
EP-4649938-A1 DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-11-19 EP disclosed
CN-106413666-A Dental cement 可乐丽则武齿科株式会社 2017-02-15 CN disclosed
US-9267043-B2 Polymerizable compound, ink cartridge containing ink including the polymerizable compound, inkjet recording apparatus using the ink cartridge, and print formed by ink including the polymerizable compound RICOH COMPANY, LTD. (JP) 2016-02-23 US disclosed
US-9267043-B2 Polymerizable compound, ink cartridge containing ink including the polymerizable compound, inkjet recording apparatus using the ink cartridge, and print formed by ink including the polymerizable compound RICOH COMPANY, LTD. (JP) 2016-02-23 US disclosed
WO-2015190099-A1 DENTAL ADHESIVE クラレノリタケデンタル株式会社 2015-12-17 WO disclosed
WO-2015190101-A1 SELF-ADHESIVE DENTAL COMPOSITE RESIN クラレノリタケデンタル株式会社 2015-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260053717-A1 CARIOUS TOOTH STRUCTURE RECOVERY AGENT, AND DENTAL ADHESIVE KIT ITGA1, TAS1R1, KATNA1 THRB 1112/4885TSHR 1960/4885ALDH1A1 954/4885
US-20180360696-A1 DENTAL ADHESIVE PTK2, CDH1, CAD THRB 1163/4885TSHR 4078/4885ALDH1A1 110/4885
US-20230270630-A1 COMPOSITION FOR DENTAL ATTACHMENT ITGA1, ITGA2, PPA1 THRB 3836/4885TSHR 4298/4885ALDH1A1 424/4885
US-10456333-B2 Dental adhesive PTK2, CDH1, CAD THRB 1163/4885TSHR 4078/4885ALDH1A1 110/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL THRB 2959/4885TSHR 4185/4885ALDH1A1 668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.