SCHEMBL17367241

SCHEMBL17367241

c1ccc(C2(c3ccccc3)c3ccccc3-c3sc4c(ccc5c6ccccc6[nH]c54)c32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
KIF11 P52732 5/20 0.37
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
GABRB2 P47870 1/20 0.35
GABRA4 P48169 1/20 0.35
GABRE P78334 1/20 0.35
GABRA6 Q16445 1/20 0.35
GABRG1 Q8N1C3 1/20 0.35
GABRG3 Q99928 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17367226 0.82 MAPT (0.42) MEN1MAPTRAB9AKMT2AKIF11
SCHEMBL29453893 0.82 MAPT (0.42) MEN1MAPTRAB9AKMT2AKIF11
SCHEMBL2603644 0.79 KIF11 (0.42) KIF11GABRPGABRDGABRA1GABRB1
SCHEMBL17367239 0.77 KDM4E (0.33) MEN1MAPTKMT2A
SCHEMBL17299618 0.74 KIF11 (0.43) MEN1MAPTKMT2AKIF11GABRP
SCHEMBL18688079 0.74 GABRP (0.42) MEN1MAPTKMT2AKIF11GABRP
SCHEMBL15840171 0.74 KIF11 (0.42) MEN1MAPTKMT2AKIF11GABRP
SCHEMBL20327438 0.73 BCHE (0.40) MEN1MAPTRAB9AKMT2AKIF11
SCHEMBL17367237 0.73 GPR3 (0.36) MEN1MAPTRAB9AKMT2APARP14
SCHEMBL20437697 0.72 KIF11 (0.43) KIF11GABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3185324-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-10-04 EP disclosed
EP-3244465-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-04-20 EP disclosed
EP-3176845-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-03-16 EP disclosed
US-11217754-B2 Organic electroluminescence device HODOGAYA CHEMICAL CO., LTD. (JP) 2022-01-04 US disclosed
EP-3389106-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2021-12-01 EP disclosed
US-10749118-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-18 US disclosed
US-10505119-B2 Organic electroluminescence device HODOGAYA CHEMICAL CO., LTD. (JP) 2019-12-10 US disclosed
US-10424742-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2019-09-24 US disclosed
US-20180362843-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2018-12-20 US disclosed
EP-3389106-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2018-10-17 EP disclosed
US-20180212153-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2018-07-26 US disclosed
US-20180026198-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2018-01-25 US disclosed
EP-3244465-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
US-20170271599-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-09-21 US disclosed
EP-3185324-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-06-28 EP disclosed
EP-3176845-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-06-07 EP disclosed
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170271599-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC43A1, KCNN4 MEN1 1521/4885MAPT 3749/4885RAB9A 3221/4885
US-10505119-B2 Organic electroluminescence device AHR, ARNT, NAT1 MEN1 1650/4885MAPT 2393/4885RAB9A 2583/4885
US-20180362843-A1 ORGANIC ELECTROLUMINESCENT DEVICE SLCO2A1, SLCO2B1, SLCO1B3 MEN1 3359/4885MAPT 1894/4885RAB9A 2134/4885
US-20180212153-A1 ORGANIC ELECTROLUMINESCENCE DEVICE TYR, SLC18A1, SLC18A3 MEN1 4018/4885MAPT 1807/4885RAB9A 2687/4885
US-10424742-B2 Organic electroluminescent device AHR, SLC43A1, KCNN4 MEN1 1521/4885MAPT 3749/4885RAB9A 3221/4885
US-11217754-B2 Organic electroluminescence device TYR, SLC18A1, SLC18A3 MEN1 4018/4885MAPT 1807/4885RAB9A 2687/4885
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CYP1A1, CRY1, CYP1B1 MEN1 127/4885MAPT 1909/4885RAB9A 1419/4885
US-10749118-B2 Heterocyclic compound and organic light-emitting device including the same CYP1A1, CRY1, CYP1B1 MEN1 127/4885MAPT 1909/4885RAB9A 1419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.