SCHEMBL14719792

SCHEMBL14719792

COCCOc1c(S(C)(=O)=O)ccc(C(=O)c2cnn(C(C)I)c2O)c1Cl

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10097307 0.92 NR3C1 (0.31) NR3C1
SCHEMBL1738355 0.83 SMN1; SMN2 (0.36) NR3C1
SCHEMBL1037206 0.83 FPR1 (0.32)
SCHEMBL8886586 0.77 NR3C1 (0.31) NR3C1
SCHEMBL9076266 0.77 EPAS1 (0.32)
SCHEMBL645624 0.75 NR3C1 (0.31) NR3C1
SCHEMBL8888375 0.75 RAB9A (0.33) NR3C1
SCHEMBL7976218 0.74 PRKAB2 (0.37)
SCHEMBL30042076 0.74 SMN1; SMN2 (0.34)
SCHEMBL1032996 0.74 SMN1; SMN2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11230717-B2 Plants having increased tolerance to herbicides BASF SE (DE) 2022-01-25 US disclosed
US-11046971-B2 Plants having increased tolerance to herbicides BASF SE 2021-06-29 US disclosed
US-20210147866-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2021-05-20 US disclosed
US-10829778-B2 Plants having increased tolerance to herbicides BASF SE (DE) 2020-11-10 US disclosed
US-10801035-B2 Plants having increased tolerance to herbicides BASF SE (DE) 2020-10-13 US disclosed
US-10294488-B2 Herbicide-metabolizing cytochrome P450 monooxygenases BASF SE (DE) 2019-05-21 US disclosed
US-20170114358-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2017-04-27 US disclosed
US-20170067075-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2017-03-09 US disclosed
US-20170029840-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2017-02-02 US disclosed
US-20150322453-A1 HERBICIDE-METABOLIZING CYTOCHROME P450 MONOOXYGENASES BASF SE (DE) 2015-11-12 US disclosed
US-20150005168-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2015-01-01 US disclosed
US-20130053243-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF SE (DE) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170029840-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES HPD, MPST, NMT2 NR3C1 3690/4885
US-20170114358-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES HPD, MPST, DNTT NR3C1 3180/4885
US-20170067075-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES HPD, MPST, DNTT NR3C1 3180/4885
US-20150005168-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES HPD, GNPAT, DNTT NR3C1 3554/4885
US-10829778-B2 Plants having increased tolerance to herbicides HPD, MPST, NMT2 NR3C1 3690/4885
US-11230717-B2 Plants having increased tolerance to herbicides HPD, MPST, DNTT NR3C1 3180/4885
US-20130053243-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES HPD, DNTT, MPST NR3C1 3573/4885
US-20210147866-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES HPD, PAH, ME3 NR3C1 4077/4885
US-10801035-B2 Plants having increased tolerance to herbicides HPD, GNPAT, DNTT NR3C1 3554/4885
US-11046971-B2 Plants having increased tolerance to herbicides HPD, MPST, DNTT NR3C1 3180/4885
US-20150322453-A1 HERBICIDE-METABOLIZING CYTOCHROME P450 MONOOXYGENASES CYP1A2, CYP3A43, CYP11B1 NR3C1 1380/4885
US-10294488-B2 Herbicide-metabolizing cytochrome P450 monooxygenases CYP1A2, CYP3A43, CYP11B1 NR3C1 1380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.