SCHEMBL17394753

SCHEMBL17394753

CCOc1ccccc1C(=O)OOC(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HCRTR1 O43613 2/20 0.53
▸ KMT2A Q03164 2/20 0.49
▸ MEN1 O00255 1/20 0.49
▸ L3MBTL1 Q9Y468 4/20 0.48
▸ MAPT P10636 3/20 0.48
▸ LMNA P02545 1/20 0.48
▸ ESR1 P03372 1/20 0.47
▸ ESR2 Q92731 1/20 0.47
▸ ALDH1A1 P00352 2/20 0.47
▸ KCNK3 O14649 1/20 0.47
▸ KCNK9 Q9NPC2 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ GAA P10253 1/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ GLA P06280 1/20 0.46
▸ NPSR1 Q6W5P4 1/20 0.46
▸ USP2 O75604 1/20 0.45
▸ ADRB2 P07550 1/20 0.45
▸ ADRB1 P08588 1/20 0.45
▸ ADRB3 P13945 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6464181 0.87 HCRTR1 (0.62) HCRTR1KMT2AMEN1L3MBTL1MAPT
SCHEMBL10324240 0.84 HCRTR1 (0.55) HCRTR1KMT2AMEN1L3MBTL1MAPT
SCHEMBL27461383 0.81 ALDH1A1 (0.70) HCRTR1KMT2AMEN1L3MBTL1MAPT
SCHEMBL7628280 0.81 HCRTR1 (0.55) HCRTR1KMT2AMEN1L3MBTL1MAPT
SCHEMBL7634707 0.81 HCRTR1 (0.55) HCRTR1KMT2AMEN1L3MBTL1MAPT
SCHEMBL7629518 0.81 HCRTR1 (0.49) HCRTR1KMT2AMEN1L3MBTL1MAPT
SCHEMBL28992535 0.80 HCRTR1 (0.62) HCRTR1KMT2AMEN1L3MBTL1MAPT
SCHEMBL4282830 0.80 HCRTR1 (0.62) HCRTR1KMT2AMEN1L3MBTL1MAPT
SCHEMBL7627703 0.79 HCRTR1 (0.54) HCRTR1KMT2AMEN1L3MBTL1MAPT
SCHEMBL15972632 0.79 ALDH1A1 (0.47) KMT2AL3MBTL1LMNAALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018145219-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ADDICTIONS BY MEANS OF AVERSIVE COUNTERCONDITIONING SERANI MOSTAZAL JORGE (CL) 2018-08-16 — — WO claimed
EP-4237396-B1 METHOD OF MITIGATING CONVERSION OF VOLATILE TERPENE SPECIES GIVAUDAN SA (CH) 2026-02-18 — — EP disclosed
US-20260027132-A1 FRAGRANCE COMPOSITIONS AND USE THEREOF FOR IMPROVING SLEEP TAKASAGO INTERNATIONAL CORPORATION (JP) 2026-01-29 — — US disclosed
EP-4237393-B1 METHOD OF CAUSING CONVERSION OF VOLATILE TERPENE SPECIES GIVAUDAN SA (CH) 2025-12-24 — — EP disclosed
US-20250333368-A1 METHOD OF MITIGATING CONVERSION OF VOLATILE TERPENE SPECIES GIVAUDAN SA (CH) 2025-10-30 — — US disclosed
US-12453736-B2 Fragrance compositions and use thereof for improving sleep TAKASAGO INTERNATIONAL CORPORATION (JP) 2025-10-28 — — US disclosed
EP-3164107-B1 LACTONE-CONTAINING COMPOSITIONS FOR MALODOR ELIMINATION TAKASAGO PERFUMERY CO LTD (JP) 2025-09-03 — — EP disclosed
US-12351546-B2 Method of mitigating conversion of volatile terpene species GIVAUDAN SA (CH) 2025-07-08 — — US disclosed
US-20250091984-A1 FRAGRANCE AND FLAVOR MATERIALS TAKASAGO INTERNATIONAL CORPORATION (JP) 2025-03-20 — — US disclosed
EP-4504693-A1 FRAGRANCE AND FLAVOR MATERIALS Takasago International Corporation (JP) 2025-02-12 — — EP disclosed
WO-2018119469-A1 FRAGRANCE AND FLAVOR MATERIALS TAKASAGO INTERNATIONAL CORPORATION (USA) (US) 2018-06-28 — — WO disclosed
WO-2018119466-A1 FRAGRANCE AND FLAVOR MATERIALS TAKASAGO INTERNATIONAL CORPORATION (USA) (US) 2018-06-28 — — WO disclosed
WO-2018119471-A1 FRAGRANCE AND FLAVOR MATERIALS TAKASAGO INTERNATIONAL CORPORATION (USA) (US) 2018-06-28 — — WO disclosed
WO-2018005839-A1 FRAGRANCE COMPOSITIONS AND METHODS OF USE THEREOF TAKASAGO INTERNATIONAL CORPORATION (USA) (US) 2018-01-04 — — WO disclosed
WO-2018005844-A1 FRAGRANCE COMPOSITIONS AND METHODS OF USE THEREOF TAKASAGO INTERNATIONAL CORPORATION (USA) (US) 2018-01-04 — — WO disclosed
WO-2017214455-A1 FRAGRANCE MATERIAL TAKASAGO INTERNATIONAL CORPORATION (USA) (US) 2017-12-14 — — WO disclosed
WO-2017214446-A1 FRAGRANCE MATERIAL TAKASAGO INTERNATIONAL CORPORATION (USA) (US) 2017-12-14 — — WO disclosed
EP-3164107-A2 LACTONE-CONTAINING COMPOSITIONS FOR MALODOR ELIMINATION Takasago International Corporation (JP) 2017-05-10 — — EP disclosed
WO-2016001761-A2 LACTONE-CONTAINING COMPOSITIONS FOR MALODOR ELIMINATION TAKASAGO INTERNATIONAL CORPORATION (JP) 2016-01-07 — — WO disclosed
US-20160000679-A1 LACTONE-CONTAINING COMPOSITIONS FOR MALODOR ELIMINATION TAKASAGO INTERNATIONAL CORPORATION (JP) 2016-01-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250091984-A1 FRAGRANCE AND FLAVOR MATERIALS TAS2R5, TAS2R8, NISCH HCRTR1 3190/4885KMT2A 1621/4885MEN1 2848/4885
US-20160000679-A1 LACTONE-CONTAINING COMPOSITIONS FOR MALODOR ELIMINATION LPO, SMOX, ME1 HCRTR1 2680/4885KMT2A 1744/4885MEN1 1476/4885
US-20260027132-A1 FRAGRANCE COMPOSITIONS AND USE THEREOF FOR IMPROVING SLEEP B2M, PER2, CHRM2 HCRTR1 345/4885KMT2A 2371/4885MEN1 4405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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