Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444075 | 0.74 | KDM4E (0.40) | LMNASMN1; SMN2MAPTKDM1AKDM4E | |
| SCHEMBL12102886 | 0.74 | CXCL12 (0.46) | LMNASMN1; SMN2MAPTKDM4EHSP90AA1 | |
| SCHEMBL8566577 | 0.74 | HTR1A (0.42) | LMNASMN1; SMN2MAPTKDM1AKDM4E | |
| SCHEMBL17397891 | 0.71 | LMNA (0.44) | LMNASMN1; SMN2MAPTKDM4EHSP90AA1 | |
| SCHEMBL15902849 | 0.68 | PDE7A (0.46) | SMN1; SMN2MAPTKDM1AKDM4EMEN1 | |
| SCHEMBL3793122 | 0.67 | TSHR (0.48) | LMNASMN1; SMN2KDM1AKDM4EMEN1 | |
| SCHEMBL8566180 | 0.67 | HTR1A (0.41) | LMNAMAPTKDM1AKDM4EMEN1 | |
| SCHEMBL8564591 | 0.67 | HTR1A (0.64) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8570726 | 0.66 | PDE4A (0.42) | LMNASMN1; SMN2MAPTKDM1AALDH1A1 | |
| SCHEMBL17302068 | 0.66 | L3MBTL1 (0.41) | LMNAMAPTKDM1AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106397453-B | New materials with aza-dibenzothiophene or aza-dibenzofuran core for PHOLEDs | 通用显示公司 | 2021-06-18 | — | — | CN | disclosed |
| EP-3689882-A1 | NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED | Universal Display Corporation (US) | 2020-08-05 | — | — | EP | disclosed |
| EP-2703405-B1 | NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED | UNIVERSAL DISPLAY CORP (US) | 2020-04-15 | — | — | EP | disclosed |
| US-9831442-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2017-11-28 | — | — | US | disclosed |
| US-20170077417-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2017-03-16 | — | — | US | disclosed |
| US-9518063-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2016-12-13 | — | — | US | disclosed |
| EP-2387576-B1 | NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED | UNIVERSAL DISPLAY CORP (US) | 2016-01-13 | — | — | EP | disclosed |
| US-20150274749-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2015-10-01 | — | — | US | disclosed |
| US-9067947-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2015-06-30 | — | — | US | disclosed |
| US-8952363-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2015-02-10 | — | — | US | disclosed |
| EP-2703405-A2 | New materials with aza-dibenzothiophene or aza-dibenzofuran core for pholed | Universal Display Corporation (US) | 2014-03-05 | — | — | EP | disclosed |
| US-20130060037-A1 | MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED | UNIVERSAL DISPLAY CORPORATION (US) | 2013-03-07 | — | — | US | disclosed |
| EP-2387576-A2 | NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED | Universal Display Corporation (US) | 2011-11-23 | — | — | EP | disclosed |
| US-20100187984-A1 | MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED | UNIVERSAL DISPLAY CORPORATION (US) | 2010-07-29 | — | — | US | disclosed |
| WO-2010083359-A2 | NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED | UNIVERSAL DISPLAY CORPORATION (US) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170077417-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | DDT, AZI2, EED | LMNA 3913/4885SMN1; SMN2 2253/4885MAPT 1165/4885 |
| US-20150274749-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | DDT, AZI2, EED | LMNA 3913/4885SMN1; SMN2 2253/4885MAPT 1165/4885 |
| US-20130060037-A1 | MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED | DDT, FZD7, BRD7 | LMNA 4455/4885SMN1; SMN2 3714/4885MAPT 1289/4885 |
| US-20100187984-A1 | MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED | DDT, FZD7, BRD7 | LMNA 4455/4885SMN1; SMN2 3714/4885MAPT 1289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.