SCHEMBL17424792

SCHEMBL17424792

C=C(CS(=O)(=O)c1ccc(C)cc1)C(=O)OCC

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
KMT2A Q03164 4/20 0.53
CA2 P00918 3/20 0.51
CA9 Q16790 3/20 0.51
RECQL P46063 1/20 0.49
GAA P10253 3/20 0.46
MAPT P10636 1/20 0.46
HSD17B10 Q99714 1/20 0.46
HSD11B1 P28845 2/20 0.45
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
LMNA P02545 1/20 0.44
PKM P14618 2/20 0.43
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17424810 0.88 ALDH1A1 (0.46) ALDH1A1KMT2ACA2CA9RECQL
SCHEMBL23095597 0.88 ALDH1A1 (0.46) ALDH1A1KMT2ACA2CA9RECQL
SCHEMBL5080063 0.88 HSD11B1 (0.58) ALDH1A1KMT2ACA9RECQLGAA
SCHEMBL17424803 0.87 ALDH1A1 (0.50) ALDH1A1KMT2ACA2CA9RECQL
SCHEMBL17424797 0.87 ALDH1A1 (0.50) ALDH1A1KMT2ACA2CA9RECQL
SCHEMBL17424790 0.87 ALDH1A1 (0.50) ALDH1A1KMT2ACA2CA9RECQL
SCHEMBL20145427 0.87 ALDH1A1 (0.50) ALDH1A1KMT2ACA2CA9RECQL
SCHEMBL30159652 0.85 ALDH1A1 (0.49) ALDH1A1KMT2ACA2CA9RECQL
SCHEMBL18214477 0.85 ALDH1A1 (0.59) ALDH1A1KMT2ACA2CA9RECQL
SCHEMBL17416312 0.85 PLA2G2C (0.47) ALDH1A1KMT2ACA2CA9RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12296031-B2 Esthetic dental filling material with high depth of cure IVOCLAR VIVADENT AG (LI) 2025-05-13 US claimed
CN-111228124-B Rapidly curing and low shrinkage stress photopolymerizable dental composites 义获嘉伟瓦登特公司 2024-04-09 CN claimed
US-20230265220-A1 Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress IVOCLAR VIVADENT AG (LI) 2023-08-24 US claimed
US-11673980-B2 Photopolymerizable dental composites with rapid curing and low shrinkage stress IVOCLAR VIVADENT AG (LI) 2023-06-13 US claimed
US-20230052305-A1 Esthetic Dental Filling Material With High Depth Of Cure IVOCLAR VIVADENT AG (LI) 2023-02-16 US claimed
EP-4124331-A1 AESTHETIC DENTAL FILLING MATERIAL WITH HIGH CURING DEPTH Ivoclar Vivadent AG (LI) 2023-02-01 EP claimed
CN-111228124-A Rapid curing and low shrinkage stress photopolymerizable dental composites 义获嘉伟瓦登特公司 2020-06-05 CN claimed
EP-3659575-A1 PHOTOPOLYMERISABLE DENTAL COMPOSITES WITH FAST CURING AND LOW SHRINKAGE STRESS Ivoclar Vivadent AG (LI) 2020-06-03 EP claimed
US-20200165363-A1 PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS IVOCLAR VIVADENT AG (LI) 2020-05-28 US claimed
US-12514791-B2 Aesthetic dental filling material having high curing depth IVOCLAR VIVADENT AG (LI) 2026-01-06 US disclosed
US-20250352435-A1 AESTHETIC DENTAL FILLING MATERIAL HAVING HIGH CURING DEPTH IVOCLAR VIVADENT AG (LI) 2025-11-20 US disclosed
US-12296031-B2 Esthetic dental filling material with high depth of cure IVOCLAR VIVADENT AG (LI) 2025-05-13 US disclosed
US-20250009608-A1 Radically Polymerizable Materials For The Production Of Dental Moldings With High Fracture Toughness IVOCLAR VIVADENT AG (LI) 2025-01-09 US disclosed
EP-4483860-A1 RADICALLY POLYMERISABLE MATERIALS FOR PRODUCING DENTAL MOULDED BODIES WITH HIGH FRACTURE TOUGHNESS Ivoclar Vivadent AG (LI) 2025-01-01 EP disclosed
EP-3091037-A1 SULFONIC ACID ESTER AS REGULATOR IN RADICAL POLYMERIZATION REACTIONS Ivoclar Vivadent AG (LI) 2016-11-09 EP disclosed
EP-3091037-A1 SULFONIC ACID ESTER AS REGULATOR IN RADICAL POLYMERIZATION REACTIONS Ivoclar Vivadent AG (LI) 2016-11-09 EP disclosed
WO-2016005534-A1 COMPOSITES HAVING A CONTROLLED NETWORK STRUCTURE IVOCLAR VIVADENT AG (LI) 2016-01-14 WO disclosed
WO-2016005540-A1 DENTAL MATERIALS HAVING DEBONDING-ON-DEMAND PROPERTIES IVOCLAR VIVADENT AG (LI) 2016-01-14 WO disclosed
EP-2965741-A1 Composites with controlled network structure Ivoclar Vivadent AG (LI) 2016-01-13 EP disclosed
EP-2965740-A1 Dental materials with debonding on demand properties Ivoclar Vivadent AG (LI) 2016-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265220-A1 Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress MMAB, ALAD, SULT1E1 ALDH1A1 355/4885KMT2A 1009/4885CA2 3658/4885
US-20250009608-A1 Radically Polymerizable Materials For The Production Of Dental Moldings With High Fracture Toughness RIF1, FANCI, MAT1A ALDH1A1 128/4885KMT2A 2200/4885CA2 3780/4885
US-11673980-B2 Photopolymerizable dental composites with rapid curing and low shrinkage stress MMAB, ALAD, SULT1E1 ALDH1A1 355/4885KMT2A 1009/4885CA2 3658/4885
US-20200165363-A1 PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS MMAB, ALAD, SULT1E1 ALDH1A1 355/4885KMT2A 1009/4885CA2 3658/4885
US-12296031-B2 Esthetic dental filling material with high depth of cure RARA, RARG, RARB ALDH1A1 49/4885KMT2A 1511/4885CA2 3940/4885
US-20230052305-A1 Esthetic Dental Filling Material With High Depth Of Cure RARA, RARG, RARB ALDH1A1 49/4885KMT2A 1511/4885CA2 3940/4885
US-20250352435-A1 AESTHETIC DENTAL FILLING MATERIAL HAVING HIGH CURING DEPTH CAD, REV1, RAD51 ALDH1A1 670/4885KMT2A 1582/4885CA2 4608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.