Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 5/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469009 | 0.90 | ABHD6 (0.34) | HTR6TAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL17469006 | 0.85 | RIPK1 (0.35) | ARPOLBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL17469008 | 0.85 | KIF11 (0.36) | ARMCL1POLBHTR6RIPK1 | |
| SCHEMBL17468801 | 0.82 | POLB (0.36) | ARMCL1POLBHRH2TAS1R3 | |
| SCHEMBL17459385 | 0.79 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL17469002 | 0.77 | ABHD6 (0.36) | HTR6MAPTRIPK1 | |
| SCHEMBL17469158 | 0.77 | GABRA1 (0.39) | AR | |
| SCHEMBL17468913 | 0.74 | CYP19A1 (0.38) | ARMAPT | |
| SCHEMBL17468798 | 0.74 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL17468915 | 0.73 | LTA4H (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |