Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | FADS1 | O60427 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469006 | 0.91 | RIPK1 (0.35) | KIF11HDAC2ARRIPK1POLB | |
| SCHEMBL17469007 | 0.85 | AR (0.38) | KIF11HTR6ARRIPK1POLB | |
| SCHEMBL17459385 | 0.82 | TAS1R3 (0.38) | HDAC2GSK3B | |
| SCHEMBL17469158 | 0.81 | GABRA1 (0.39) | AR | |
| SCHEMBL17468800 | 0.80 | ALDH1A1 (0.35) | FADS1 | |
| SCHEMBL17468913 | 0.79 | CYP19A1 (0.38) | AR | |
| SCHEMBL17468801 | 0.79 | POLB (0.36) | KIF11HDAC2ARPOLBMCL1 | |
| SCHEMBL17468799 | 0.77 | ALDH1A1 (0.40) | — | |
| SCHEMBL17468915 | 0.76 | LTA4H (0.31) | GSK3BLDHAFADS1 | |
| SCHEMBL17469157 | 0.75 | MAOB (0.38) | FFAR1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |