Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17494918 | 0.82 | CYP3A4 (0.35) | LMNAKDM4EMAPTNPSR1HTT | |
| SCHEMBL18357557 | 0.80 | MAPT (0.38) | LMNAKDM4EMAPTNPSR1HTT | |
| SCHEMBL22779514 | 0.74 | RAB9A (0.33) | LMNAALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL9952302 | 0.73 | ALDH1A1 (0.59) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL29934119 | 0.71 | POLB (0.33) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL17494931 | 0.71 | LMNA (0.42) | LMNAKDM4EMAPTNPSR1HTT | |
| SCHEMBL5774586 | 0.67 | NCOA1 (0.41) | LMNAKDM4EMAPTNPSR1HTT | |
| SCHEMBL4017052 | 0.67 | ALDH1A1 (0.51) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL9952880 | 0.67 | ALDH1A1 (0.60) | LMNAKDM4EMAPTNPSR1MEN1 | |
| SCHEMBL3284881 | 0.67 | LMNA (0.44) | LMNAMAPTHTTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180341-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-04-27 | — | — | EP | disclosed |
| CN-107735396-B | Pesticidally active polycyclic derivatives with sulfur-containing substituents | 先正达参股股份有限公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-107531704-B | Pesticidally active polycyclic derivatives with sulfur-substituted five-membered ring heterocycles | 先正达参股股份有限公司 | 2021-01-01 | — | — | CN | disclosed |
| EP-3317276-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-16 | — | — | EP | disclosed |
| EP-3377489-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-10-07 | — | — | EP | disclosed |
| EP-3377489-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-10-07 | — | — | EP | disclosed |
| CN-111646989-A | Pesticidally active tetracyclic derivatives with sulfur-containing substituents | 先正达参股股份有限公司 | 2020-09-11 | — | — | CN | disclosed |
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-18 | — | — | US | disclosed |
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-18 | — | — | US | disclosed |
| US-10730872-B2 | Pesticidally active heterocyclic derivatives with sulphur containing sustitutents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-04 | — | — | US | disclosed |
| US-20170233389-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-17 | — | — | US | disclosed |
| US-20170233389-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-17 | — | — | US | disclosed |
| EP-3180341-A2 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | Syngenta Participations AG (CH) | 2017-06-21 | — | — | EP | disclosed |
| WO-2017001314-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | WO | disclosed |
| WO-2017001314-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | WO | disclosed |
| WO-2016169882-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-27 | — | — | WO | disclosed |
| WO-2016169882-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR SUBSTITUTED FIVE MEMBERED RING HETEROCYLES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-27 | — | — | WO | disclosed |
| WO-2016142326-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-15 | — | — | WO | disclosed |
| WO-2016023954-A2 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-18 | — | — | WO | disclosed |
| WO-2016023954-A2 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233389-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | LMNA 4417/4885KDM4E 2839/4885MAPT 797/4885 |
| US-10730872-B2 | Pesticidally active heterocyclic derivatives with sulphur containing sustitutents | TST, DDT, SULT1A1 | LMNA 4573/4885KDM4E 3181/4885MAPT 233/4885 |
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | DDT, SQOR, ACHE | LMNA 4369/4885KDM4E 3255/4885MAPT 531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.