SCHEMBL17600535

SCHEMBL17600535

O=C(Cc1ccc(C2(C(F)(F)F)N=N2)cc1)Cc1ccc(C2(C(F)(F)F)N=N2)cc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.49
GABRA1 P14867 3/20 0.41
GABRB2 P47870 2/20 0.41
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
RXRA P19793 4/20 0.36
RXRB P28702 4/20 0.36
RXRG P48443 4/20 0.36
CES1 P23141 1/20 0.35
NOS1 P29475 2/20 0.35
DUSP3 P51452 1/20 0.33
ORAI1 Q96D31 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
SIRT2 Q8IXJ6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19399250 0.91 KIF11 (0.43) KIF11GABRA1GABRB2GABRG2GABRB3
SCHEMBL24862586 0.89 KIF11 (0.42) KIF11GABRA1GABRB2GABRG2GABRB3
SCHEMBL16050172 0.88 RXRA (0.49) KIF11RXRARXRBRXRG
SCHEMBL992639 0.79 GABRA1 (0.47) KIF11GABRA1GABRB2GABRG2GABRB3
SCHEMBL20844363 0.79 KIF11 (0.43) KIF11GABRA1GABRB2GABRG2GABRB3
SCHEMBL17600534 0.79 YWHAG (0.44) KIF11GABRA1GABRB2NOS1
SCHEMBL17791489 0.78 FFAR1 (0.49) KIF11RXRARXRBRXRG
SCHEMBL2535263 0.77 KIF11 (0.42) KIF11GABRA1GABRB2GABRG2GABRB3
SCHEMBL17865332 0.77 ALDH1A1 (0.47) KIF11GABRA1GABRB2GABRG2GABRB3
SCHEMBL22632172 0.76 KMT2A (0.49) KIF11SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240336599-A1 PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS PROMERUS, LLC (US) 2024-10-10 US claimed
EP-3433884-B1 DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF PROMERUS LLC (US) 2023-01-11 EP claimed
US-10693072-B2 Diazirine containing organic electronic compositions and device thereof PROMERUS, LLC (US) 2020-06-23 US claimed
US-10303060-B2 Diazirine compounds and compositions derived therefrom PROMERUS, LLC (US) 2019-05-28 US claimed
US-20190157558-A1 DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF PROMERUS, LLC (US) 2019-05-23 US claimed
US-10256409-B2 Diazirine containing organic electronic compositions and device thereof PROMERUS, LLC (US) 2019-04-09 US claimed
EP-3433884-A1 DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF Promerus, LLC (US) 2019-01-30 EP claimed
US-20180186747-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM PROMERUS, LLC (US) 2018-07-05 US claimed
US-9938241-B2 Diazirine compounds and compositions derived therefrom PROMERUS, LLC (US) 2018-04-10 US claimed
US-20170279048-A1 DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF PROMERUS, LLC (US) 2017-09-28 US claimed
EP-3197881-A1 DIAZIRINE COMPOUNDS AS PHOTOCROSSLINKERS AND PHOTOIMAGEABLE COMPOSITIONS COMPRISING THEM Promerus, LLC (US) 2017-08-02 EP claimed
WO-2016049123-A1 DIAZIRINE COMPOUNDS AS PHOTOCROSSLINKERS AND PHOTOIMAGEABLE COMPOSITIONS COMPRISING THEM PROMERUS, LLC (US) 2016-03-31 WO claimed
US-20160083352-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM SUMITOMO BAKELITE CO., LTD. (JP) 2016-03-24 US claimed
US-20240336599-A1 PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS PROMERUS, LLC (US) 2024-10-10 US disclosed
EP-3433884-B1 DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF PROMERUS LLC (US) 2023-01-11 EP disclosed
EP-3433884-B1 DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF PROMERUS LLC (US) 2023-01-11 EP disclosed
US-20180186747-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM PROMERUS, LLC (US) 2018-07-05 US disclosed
US-20170279048-A1 DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF PROMERUS, LLC (US) 2017-09-28 US disclosed
US-20170279048-A1 DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF PROMERUS, LLC (US) 2017-09-28 US disclosed
WO-2016049123-A1 DIAZIRINE COMPOUNDS AS PHOTOCROSSLINKERS AND PHOTOIMAGEABLE COMPOSITIONS COMPRISING THEM PROMERUS, LLC (US) 2016-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240336599-A1 PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS PUF60, FTO, PARN KIF11 2032/4885GABRA1 208/4885GABRB2 353/4885
US-20160083352-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM RDX, AOX1, ALDH1A2 KIF11 2915/4885GABRA1 1904/4885GABRB2 2144/4885
US-20180186747-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM ZYX, AOX1, RDX KIF11 2025/4885GABRA1 1150/4885GABRB2 1211/4885
US-10303060-B2 Diazirine compounds and compositions derived therefrom ZYX, AOX1, RDX KIF11 2025/4885GABRA1 1150/4885GABRB2 1211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.