Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19399248 | 0.92 | THRA (0.40) | KIF11THRBTHRANPC1RAB9A | |
| SCHEMBL17791489 | 0.84 | FFAR1 (0.49) | KIF11 | |
| SCHEMBL17865332 | 0.83 | ALDH1A1 (0.47) | KIF11NPC1RAB9ANOS1KDM4E | |
| SCHEMBL20844363 | 0.82 | KIF11 (0.43) | KIF11L3MBTL1SLC5A1SLC5A2NOS1 | |
| SCHEMBL19733925 | 0.81 | KIF11 (0.43) | KIF11NOS1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL17865303 | 0.80 | KIF11 (0.47) | KIF11NPC1RAB9AL3MBTL1NOS1 | |
| SCHEMBL17625659 | 0.79 | NPC1 (0.41) | THRBTHRANPC1RAB9AL3MBTL1 | |
| SCHEMBL17625245 | 0.76 | NPC1 (0.47) | THRBTHRANPC1RAB9AL3MBTL1 | |
| SCHEMBL17600535 | 0.76 | KIF11 (0.49) | KIF11NOS1GABRA1GABRB2DUSP3 | |
| SCHEMBL2380170 | 0.75 | KIF11 (0.51) | KIF11NOS1ALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240336599-A1 | PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS | PROMERUS, LLC (US) | 2024-10-10 | — | — | US | claimed |
| EP-3433884-B1 | DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF | PROMERUS LLC (US) | 2023-01-11 | — | — | EP | claimed |
| US-10693072-B2 | Diazirine containing organic electronic compositions and device thereof | PROMERUS, LLC (US) | 2020-06-23 | — | — | US | claimed |
| US-10303060-B2 | Diazirine compounds and compositions derived therefrom | PROMERUS, LLC (US) | 2019-05-28 | — | — | US | claimed |
| US-20190157558-A1 | DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF | PROMERUS, LLC (US) | 2019-05-23 | — | — | US | claimed |
| US-10256409-B2 | Diazirine containing organic electronic compositions and device thereof | PROMERUS, LLC (US) | 2019-04-09 | — | — | US | claimed |
| US-20180186747-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | PROMERUS, LLC (US) | 2018-07-05 | — | — | US | claimed |
| US-9938241-B2 | Diazirine compounds and compositions derived therefrom | PROMERUS, LLC (US) | 2018-04-10 | — | — | US | claimed |
| US-20170279048-A1 | DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF | PROMERUS, LLC (US) | 2017-09-28 | — | — | US | claimed |
| US-20160083352-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | SUMITOMO BAKELITE CO., LTD. (JP) | 2016-03-24 | — | — | US | claimed |
| US-20240336599-A1 | PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS | PROMERUS, LLC (US) | 2024-10-10 | — | — | US | disclosed |
| EP-3433884-B1 | DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF | PROMERUS LLC (US) | 2023-01-11 | — | — | EP | disclosed |
| US-10693072-B2 | Diazirine containing organic electronic compositions and device thereof | PROMERUS, LLC (US) | 2020-06-23 | — | — | US | disclosed |
| US-10693072-B2 | Diazirine containing organic electronic compositions and device thereof | PROMERUS, LLC (US) | 2020-06-23 | — | — | US | disclosed |
| US-10303060-B2 | Diazirine compounds and compositions derived therefrom | PROMERUS, LLC (US) | 2019-05-28 | — | — | US | disclosed |
| US-20180186747-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | PROMERUS, LLC (US) | 2018-07-05 | — | — | US | disclosed |
| US-20180186747-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | PROMERUS, LLC (US) | 2018-07-05 | — | — | US | disclosed |
| US-20170279048-A1 | DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF | PROMERUS, LLC (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170279048-A1 | DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF | PROMERUS, LLC (US) | 2017-09-28 | — | — | US | disclosed |
| WO-2016049123-A1 | DIAZIRINE COMPOUNDS AS PHOTOCROSSLINKERS AND PHOTOIMAGEABLE COMPOSITIONS COMPRISING THEM | PROMERUS, LLC (US) | 2016-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336599-A1 | PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS | PUF60, FTO, PARN | KIF11 2032/4885THRB 4537/4885THRA 3583/4885 |
| US-20160083352-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | RDX, AOX1, ALDH1A2 | KIF11 2915/4885THRB 3732/4885THRA 2751/4885 |
| US-20180186747-A1 | DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM | ZYX, AOX1, RDX | KIF11 2025/4885THRB 3255/4885THRA 2736/4885 |
| US-10303060-B2 | Diazirine compounds and compositions derived therefrom | ZYX, AOX1, RDX | KIF11 2025/4885THRB 3255/4885THRA 2736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.