SCHEMBL1760113

SCHEMBL1760113

COCCC(=O)OCCO

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.43
ADRA2A P08913 1/20 0.43
ADRA1A P35348 1/20 0.43
MAPT P10636 1/20 0.41
BLM P54132 1/20 0.41
DGKA P23743 1/20 0.40
TSHR P16473 5/20 0.38
ALDH1A1 P00352 1/20 0.37
ACHE P22303 1/20 0.35
DNM1 Q05193 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
HTR2C P28335 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12199291 0.87 DGKA (0.50) ADRA2AADRA1AMAPTBLMDGKA
SCHEMBL407271 0.86 MGLL (0.49) MGLLADRA2AADRA1AMAPTBLM
SCHEMBL22113257 0.83 ADRA2A (0.42) MGLLADRA2AADRA1AMAPTBLM
SCHEMBL475320 0.82 ADRA2A (0.52) MGLLADRA2AADRA1AMAPTBLM
SCHEMBL141329 0.81 DGKA (0.50) ADRA2AADRA1AMAPTBLMDGKA
SCHEMBL28146111 0.81 DGKA (0.45) MGLLADRA2AADRA1AMAPTBLM
SCHEMBL12846426 0.81 TSHR (0.62) MGLLADRA2AADRA1AMAPTBLM
SCHEMBL28222618 0.81 ALDH1A1 (0.52) ADRA2AADRA1AMAPTBLMDGKA
SCHEMBL24465441 0.80 TSHR (0.36) ADRA2AADRA1AMAPTBLMDGKA
SCHEMBL26330790 0.80 MGLL (0.37) MGLLADRA2AADRA1AMAPTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230149521-A1 METHODS OF TREATING VIRAL INFECTIONS USING ARGINASE BIO CANCER TREAT INTERNATIONAL LIMITED (CN) 2023-05-18 US disclosed
EP-4005590-A1 METHODS AND COMPOSITIONS FOR MODULATING THE IMMUNE SYSTEM WITH ARGINASE I Bio-Cancer Treatment International Ltd. (CN) 2022-06-01 EP disclosed
EP-3137103-B1 METHODS AND COMPOSITIONS FOR MODULATING THE IMMUNE SYSTEM WITH ARGINASE I BIO CANCER TREAT INTERNATIONAL LTD (CN) 2021-10-20 EP disclosed
US-20200061165-A1 METHODS AND COMPOSITIONS FOR MODULATING THE IMMUNE SYSTEM WITH ARGINASE I BIO-CANCER TREATMENT INTERNATIONAL LIMITED (HK) 2020-02-27 US disclosed
US-20180085440-A1 METHODS AND COMPOSITIONS FOR MODULATING THE IMMUNE SYSTEM WITH ARGINASE I BIO-CANCER TREATMENT INTERNATIONAL LIMITED (HK) 2018-03-29 US disclosed
US-9867875-B2 Methods and compositions for modulating the immune system with Arginase I BIO-CANCER TREATMENT INTERNATIONAL LIMITED (HK) 2018-01-16 US disclosed
US-9789169-B2 Methods and compositions for modulating the immune system with arginase I BIO-CANCER TREATMENT INTERNATIONAL LIMITED (HK) 2017-10-17 US disclosed
US-20160367648-A1 METHODS AND COMPOSITIONS FOR MODULATING THE IMMUNE SYSTEM WITH ARGINASE I BIO-CANCER TREATMENT INTERNATIONAL LIMITED (HK) 2016-12-22 US disclosed
US-20150315561-A1 Methods and Compositions for Modulating the Immune System with Arginase I BIO-CANCER TREATMENT INTERNATIONAL LIMITED (HK) 2015-11-05 US disclosed
US-20120263739-A1 ANTI INTEGRIN ANTIBODIES LINKED TO NANOPARTICLES LOADED WITH CHEMOTHERAPEUTIC AGENTS MERCK PATENT GMBH (DE) 2012-10-18 US disclosed
US-7037425-B2 Mesoporous membrane collector and separator for airborne pathogen detection PURDUE RESEARCH FOUNDATION (US) 2006-05-02 US disclosed
EP-1453591-A4 MESOPOROUS MEMBRANE COLLECTOR AND SEPARATOR FOR AIRBORNE PATHOGEN DETECTION PURDUE RESEARCH FOUNDATION (US) 2006-03-08 EP disclosed
US-20050277586-A1 Peptide chemically modified with polyethylene glycol MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2005-12-15 US disclosed
EP-1493748-A1 PEPTIDE CHEMICALLY MODIFIED WITH POLYETHYLENE GLYCOL MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2005-01-05 EP disclosed
EP-1453591-A1 MESOPOROUS MEMBRANE COLLECTOR AND SEPARATOR FOR AIRBORNE PATHOGEN DETECTION PURDUE RESEARCH FOUNDATION (US) 2004-09-08 EP disclosed
US-20030222012-A1 Mesoporous membrane collector and separator for airborne pathogen detection PURDUE RESEARCH FOUNDATION (US) 2003-12-04 US disclosed
US-6602952-B1 Hydrogels, which are cross-linked polymers that swell in water, have potential as drug delivery vehicles SHEARWATER CORPORATION 2003-08-05 US disclosed
WO-2003049840-A1 MESOPOROUS MEMBRANE COLLECTOR AND SEPARATOR FOR AIRBORNE PATHOGEN DETECTION PURDUE RESEARCH FOUNDATION (US) 2003-06-19 WO disclosed
EP-1223986-A2 HYDROGELS DERIVED FROM CHITOSAN AND POLY(ETHYLENE GLYCOL) Shearwater Corporation (US) 2002-07-24 EP disclosed
WO-2001000246-A2 HYDROGELS DERIVED FROM CHITOSAN AND POLY(ETHYLENE GLYCOL) SHEARWATER CORPORATION (US) 2001-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149521-A1 METHODS OF TREATING VIRAL INFECTIONS USING ARGINASE ARG1, ARG2, OAT MGLL 322/4885ADRA2A 3005/4885ADRA1A 2873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.