Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.49 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.49 |
| ▸ | ENTPD1 | P49961 | 3/20 | 0.48 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.48 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.47 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17918390 | 1.00 | P2RX3 (0.49) | P2RX3P2RX2P2RX1ENTPD1P2RY1 | |
| SCHEMBL17612662 | 0.92 | FBP1 (0.50) | ENTPD1P2RY1P2RY2SRCSMN1; SMN2 | |
| SCHEMBL32663634 | 0.79 | TAS1R3 (0.55) | P2RY1P2RY2SRCSMN1; SMN2RNASEL | |
| SCHEMBL17612666 | 0.78 | ADK (0.53) | — | |
| SCHEMBL17612674 | 0.77 | ADK (0.52) | — | |
| SCHEMBL17612661 | 0.74 | AHCY (0.49) | SMN1; SMN2 | |
| SCHEMBL17612648 | 0.73 | ADK (0.45) | — | |
| SCHEMBL31338602 | 0.73 | TGM2 (0.47) | P2RX3P2RY2 | |
| SCHEMBL14403362 | 0.72 | ADK (0.68) | P2RY1P2RY2SRCALDH1A1SMN1; SMN2 | |
| SCHEMBL17806719 | 0.72 | DNPH1 (0.47) | ENTPD1P2RY1P2RY2SRCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9289398-B2 | Methods for the production of functional protein from DNA having a nonsense mutation and the treatment of disorders associated therewith | PTC THERAPEUTICS, INC. (US) | 2016-03-22 | — | — | US | disclosed |