SCHEMBL17625947

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17626330	0.85	ALDH1A1 (0.43)	AGERHTTPTGDR2HRH3TAAR1
	SCHEMBL17628672	0.83	HTT (0.54)	HTTPTGDR2ALDH1A1MAPTL3MBTL1
	SCHEMBL17626170	0.80	HTT (0.42)	HTTPTGDR2ALDH1A1MAPTL3MBTL1
	SCHEMBL19626591	0.73	PTGDR2 (0.58)	AGERHTTPTGDR2HRH3ALDH1A1
	SCHEMBL19625415	0.73	HTT (0.47)	AGERHTTPTGDR2HRH3ALDH1A1
	SCHEMBL17625973	0.71	KDM4E (0.40)	HTTPTGDR2ALDH1A1POLBMAPT
	SCHEMBL468178	0.69	GPR84 (0.43)	ALDH1A1MAPT
	SCHEMBL28295966	0.68	HRH3 (0.39)	AGERHRH3TAAR1MAPTL3MBTL1
	SCHEMBL17626111	0.67	L3MBTL1 (0.40)	PTGDR2ALDH1A1L3MBTL1KDM4ENPC1
	SCHEMBL17626152	0.67	PTGDR2 (0.37)	PTGDR2SLC2A1L3MBTL1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.