Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.78 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 7/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | NPC1 | O15118 | 4/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.74 |
| ▸ | FLT3 | P36888 | 3/20 | 0.74 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.74 |
| ▸ | RAB9A | P51151 | 3/20 | 0.74 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.74 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29738723 | 1.00 | MAOB (0.78) | MAOBCYP19A1MAPTCYP3A4MEN1 | |
| SCHEMBL4650052 | 0.88 | CYP3A4 (0.68) | MAOBCYP19A1MAPTCYP3A4MEN1 | |
| Apigenin Dimethylether SCHEMBL29392759 | 0.87 | MAOB (1.00) | MAOBCYP19A1MAPTCYP3A4MEN1 | |
| Apigenin Dimethylether SCHEMBL1176691 | 0.87 | MAOB (1.00) | MAOBCYP19A1MAPTCYP3A4MEN1 | |
| Acacetin SCHEMBL29387049 | 0.85 | CYP1B1 (1.00) | MAOBCYP19A1MAPTCYP3A4MEN1 | |
| Acacetin SCHEMBL107712 | 0.85 | CYP1B1 (1.00) | MAOBCYP19A1MAPTCYP3A4MEN1 | |
| SCHEMBL3825575 | 0.84 | AR (0.80) | MAOBCYP19A1MAPTCYP3A4MEN1 | |
| SCHEMBL12636899 | 0.84 | AR (1.00) | MAOBMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL157490 | 0.84 | AR (1.00) | MAOBCYP19A1MAPTCYP3A4MEN1 | |
| SCHEMBL29360924 | 0.84 | CYP1B1 (0.75) | MAPTCYP3A4MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110123653-A1 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2011-05-26 | — | — | US | claimed |
| EP-1883300-A2 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | Rutgers, The State University of New Jersey (US) | 2008-02-06 | — | — | EP | claimed |
| US-20070042972-A1 | Compositions and methods for optimizing exercise recovery | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2007-02-22 | — | — | US | claimed |
| WO-2006127996-A2 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2006-11-30 | — | — | WO | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| EP-1214040-A4 | EXTRACTS OF ORANGE PEEL FOR PREVENTION AND TREATMENT OF CANCER | UNIV RUTGERS (US) | 2004-06-23 | — | — | EP | claimed |
| EP-1214040-A1 | EXTRACTS OF ORANGE PEEL FOR PREVENTION AND TREATMENT OF CANCER | Rutgers, The State University (US) | 2002-06-19 | — | — | EP | claimed |
| WO-2001021137-A1 | EXTRACTS OF ORANGE PEEL FOR PREVENTION AND TREATMENT OF CANCER | RUTGERS, THE STATE UNIVERSITY (US) | 2001-03-29 | — | — | WO | claimed |
| US-10165792-B2 | Hunger minimized juice fasting system | NARASIMHAN SUDARSHAN (US) | 2019-01-01 | — | — | US | disclosed |
| EP-2730431-B1 | Rubber composition and tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2017-06-28 | — | — | EP | disclosed |
| US-20160366925-A1 | Hunger Minimized Juice Fasting System | NARASIMHAN SUDARSHAN (US) | 2016-12-22 | — | — | US | disclosed |
| US-9492418-B2 | Inhibitors of PFKFB3 for cancer therapy | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2016-11-15 | — | — | US | disclosed |
| US-9492418-B2 | Inhibitors of PFKFB3 for cancer therapy | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2016-11-15 | — | — | US | disclosed |
| US-20140135433-A1 | TIRE WITH RUBBER CONTAINING FLAVONE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2014-05-15 | — | — | US | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
| EP-1298115-A1 | PROCESS FOR THE PREPARATION OF POLYHYDRIC ALCOHOLS | National Institute of Advanced Industrial Science and Technology (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-20020157939-A1 | Process for preparation of polyhydric alcohols | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2002-10-31 | — | — | US | disclosed |
| EP-1214040-A1 | EXTRACTS OF ORANGE PEEL FOR PREVENTION AND TREATMENT OF CANCER | Rutgers, The State University (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021137-A1 | EXTRACTS OF ORANGE PEEL FOR PREVENTION AND TREATMENT OF CANCER | RUTGERS, THE STATE UNIVERSITY (US) | 2001-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070042972-A1 | Compositions and methods for optimizing exercise recovery | GYS1, PYGM, PRDX5 | MAOB 878/4885CYP19A1 257/4885MAPT 4515/4885 |
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | MAOB 652/4885CYP19A1 460/4885MAPT 4313/4885 |
| US-20110123653-A1 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | GYS1, PYGM, PRDX5 | MAOB 878/4885CYP19A1 257/4885MAPT 4515/4885 |
| US-20020157939-A1 | Process for preparation of polyhydric alcohols | ADH1C, ADH1A, ADH5 | MAOB 495/4885CYP19A1 4113/4885MAPT 3759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.