Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17666638 | 0.80 | MEN1 (0.40) | SMN1; SMN2LSSRAB9ANPC1 | |
| SCHEMBL17676104 | 0.75 | LMNA (0.35) | AAK1LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15264021 | 0.73 | KCNH2 (0.42) | LMNASMN1; SMN2PPARARAB9ANPC1 | |
| SCHEMBL19112386 | 0.73 | PDK2 (0.47) | ALDH1A1SMN1; SMN2PPARANPC1PDK2 | |
| SCHEMBL15067764 | 0.72 | MAPT (0.42) | LMNAALDH1A1MAPTSMN1; SMN2LSS | |
| SCHEMBL15067149 | 0.72 | RXFP1 (0.52) | LMNAALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL30264506 | 0.71 | LTB4R (0.46) | MAPTSMN1; SMN2PPARARAB9ANPC1 | |
| SCHEMBL2847467 | 0.71 | HCAR3 (0.48) | AAK1MAPTHDAC1HDAC8HDAC6 | |
| SCHEMBL14679116 | 0.71 | L3MBTL1 (0.53) | LMNAALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL22280529 | 0.70 | HDAC2 (0.54) | LMNAALDH1A1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309211-B2 | Arylalkene derivatives and use thereof as selective estrogen receptor modulators | CENTAURUS BIOPHARMA CO., LTD. (CN) | 2016-04-12 | — | — | US | disclosed |