Sugi Predict

Sugi Predict / Compounds / SCHEMBL1768425

SCHEMBL1768425

SCHEMBL1768425

NC(Cc1c[nH]c2cc(C(F)(F)F)ccc12)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.61
▸ MEN1 O00255 3/20 0.61
▸ KDM4E B2RXH2 2/20 0.61
▸ LMNA P02545 2/20 0.61
▸ MAPT P10636 2/20 0.61
▸ TSHR P16473 2/20 0.61
▸ BLM P54132 2/20 0.61
▸ PMP22 Q01453 2/20 0.61
▸ MPO P05164 1/20 0.61
▸ HIF1A Q16665 1/20 0.61
▸ PTPRA P18433 1/20 0.61
▸ CYP2C19 P33261 1/20 0.59
▸ ALDH1A1 P00352 2/20 0.57
▸ CYP3A4 P08684 1/20 0.57
▸ HTR1A P08908 1/20 0.57
▸ ADORA3 P0DMS8 1/20 0.57
▸ ALOX15 P16050 1/20 0.57
▸ NFKB1 P19838 1/20 0.57
▸ HTR2A P28223 1/20 0.57
▸ HTR2C P28335 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30317386 1.00 KMT2A (0.61) KMT2AMEN1KDM4ELMNAMAPT
SCHEMBL1768423 1.00 KMT2A (0.61) KMT2AMEN1KDM4ELMNAMAPT
Hydrochloric Acid SCHEMBL28739154 0.99 KMT2A (0.60) KMT2AMEN1KDM4ELMNAMAPT
SCHEMBL31369743 0.90 KMT2A (0.68) KMT2AMEN1KDM4ELMNAMAPT
SCHEMBL27529291 0.88 KMT2A (0.63) KMT2AMEN1KDM4ELMNAMAPT
SCHEMBL27529289 0.88 KMT2A (0.63) KMT2AMEN1KDM4ELMNAMAPT
SCHEMBL20829890 0.85 SOS1 (0.51) KMT2AMEN1KDM4ELMNAMAPT
Hydrochloric Acid SCHEMBL29616595 0.84 SOS1 (0.50) KMT2AMEN1KDM4ELMNAMAPT
SCHEMBL248870 0.83 KMT2A (0.66) KMT2AMEN1KDM4ELMNAMAPT
SCHEMBL30381733 0.83 KMT2A (0.66) KMT2AMEN1KDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 390 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 — — US claimed
US-20240188613-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-06-13 — — US claimed
US-20240090547-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-03-21 — — US claimed
US-20240065302-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-02-29 — — US claimed
CN-116963609-A Sweetener composition comprising mogrosides and uses thereof 弗门尼舍公司 2023-10-27 — — CN claimed
EP-4258897-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF Firmenich Incorporated (US) 2023-10-18 — — EP claimed
EP-4258895-A1 SWEETENER COMPOSTIONS COMPRISING SIAMENOSIDE I AND USES THEREOF Firmenich Incorporated (US) 2023-10-18 — — EP claimed
EP-4258896-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF Firmenich Incorporated (US) 2023-10-18 — — EP claimed
WO-2022155668-A1 SWEETENER COMPOSTIONS COMPRISING SIAMENOSIDE I AND USES THEREOF FIRMENICH INCORPORATED (US) 2022-07-21 — — WO claimed
WO-2022155667-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED (US) 2022-07-21 — — WO claimed
WO-2022155669-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED (US) 2022-07-21 — — WO claimed
US-20180086751-A1 SWEETENER COMPOSITION SENOMYX, INC. 2018-03-29 — — US claimed
US-20170354175-A1 SWEETENER COMPOSITION SENOMYX, INC. 2017-12-14 — — US claimed
US-20170105432-A1 SWEETENER AND FLAVOR ENHANCER FORMULATIONS SENOMYX, INC. 2017-04-20 — — US claimed
US-20260144275-A1 EXTRUSION METHODS AND FLAVORED PRODUCTS FORMED THEREBY FIRMENICH SA (CH) 2026-05-28 — — US disclosed
US-12635718-B2 Flavanone derivatives and their use as sweetness enhancers FIRMENICH SA (CH) 2026-05-26 — — US disclosed
CN-122028804-A Flavanone compounds and their use as flavor modifiers 弗门尼舍有限公司 2026-05-12 — — CN disclosed
US-4256730-A DENTIFRICES, MOUTHWASH, 6-METHYLOXATHIAZINONE DIOXIDE SWEETENER THE PROCTER & GAMBLE COMPANY (US) 1981-03-17 — — US disclosed
EP-0008480-A1 Sweetened oral compositions, preferably toothpastes or mouthwash compositions THE PROCTER & GAMBLE COMPANY (US) 1980-03-05 — — EP disclosed
US-4080440-A MIXING CALCIUM SALT WITH A PHOSPHATE SALT, APPLYING TO TEETH THE PROCTER & GAMBLE COMPANY (US) 1978-03-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144275-A1 EXTRUSION METHODS AND FLAVORED PRODUCTS FORMED THEREBY MYCBP, VIM, MAFG KMT2A 2174/4885MEN1 317/4885KDM4E 911/4885
US-20180086751-A1 SWEETENER COMPOSITION TAS2R50, TAS1R2, TAS2R10 KMT2A 605/4885MEN1 232/4885KDM4E 2019/4885
US-20170105432-A1 SWEETENER AND FLAVOR ENHANCER FORMULATIONS TAS2R50, TAS2R10, TAS2R40 KMT2A 600/4885MEN1 281/4885KDM4E 980/4885
US-12635718-B2 Flavanone derivatives and their use as sweetness enhancers TAS2R10, TAS2R20, TAS2R7 KMT2A 3381/4885MEN1 1914/4885KDM4E 3632/4885
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 KMT2A 3415/4885MEN1 4354/4885KDM4E 3586/4885
US-20170354175-A1 SWEETENER COMPOSITION TAS1R2, TAS1R1, TAS2R50 KMT2A 763/4885MEN1 282/4885KDM4E 2566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.