Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 2-Allylphenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 2/20 | 0.37 |
| ▸ | GABRB2 known ✓ | P47870 | 2/20 | 0.37 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.32 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.32 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.32 |
| ▸ | XDH known ✓ | P47989 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2872983 | 0.85 | ICAM1 (0.39) | ALDH1A1LMNAKDM4EADRB2HTR1A | |
| 2-Allylphenol SCHEMBL1777272 | 0.79 | AKR1B1 (0.41) | POLBGABRA1GABRB2AKR1B1ALDH1A1 | |
| 2-Allylphenol SCHEMBL28240228 | 0.78 | POLB (0.56) | POLBGABRA1GABRB2AKR1B1CA12 | |
| 2-Allylphenol SCHEMBL325760 | 0.78 | POLB (0.54) | POLBGABRA1GABRB2AKR1B1CA12 | |
| SCHEMBL30753415 | 0.77 | BID (0.45) | HTTKDM4EMGLL | |
| SCHEMBL28036281 | 0.77 | BID (0.45) | HTTKDM4EMGLL | |
| 2-Allylphenol SCHEMBL17304231 | 0.76 | POLB (0.53) | POLBGABRA1GABRB2AKR1B1CA12 | |
| 2-Allylphenol SCHEMBL27738263 | 0.76 | POLB (0.53) | POLBGABRA1GABRB2AKR1B1CA12 | |
| 2-Allylphenol SCHEMBL17304230 | 0.76 | POLB (0.53) | POLBGABRA1GABRB2AKR1B1CA12 | |
| SCHEMBL18378452 | 0.76 | ICAM1 (0.39) | ALDH1A1LMNAKDM4EADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943065-B2 | Conductive carbon nanotube-polymer composite | ARKEMA FRANCE (FR) | 2011-05-17 | — | — | US | disclosed |
| US-20090200517-A1 | CONDUCTIVE CARBON NANOTUBE-POLYMER COMPOSITE | ARKEMA FRANCE (FR) | 2009-08-13 | — | — | US | disclosed |
| CN-101421338-A | Conductive carbon nanotube-polymer composite | ARKEMA FRANCE (FR) | 2009-04-29 | — | — | CN | disclosed |
| EP-2013266-A2 | CONDUCTIVE CARBON NANOTUBE-POLYMER COMPOSITE | Arkema France (FR) | 2009-01-14 | — | — | EP | disclosed |
| EP-1623437-B1 | CONDUCTIVE CARBON NANOTUBE-POLYMER COMPOSITE | CARBON NANOTECHNOLOGIES INC (US) | 2007-12-05 | — | — | EP | disclosed |
| WO-2007119172-A2 | CONDUCTIVE CARBON NANOTUBE-POLYMER COMPOSITE | ARKEMA FRANCE (FR) | 2007-10-25 | — | — | WO | disclosed |
| EP-1845124-A1 | Conductive carbon nanotube-polymer composite | ARKEMA FRANCE (FR) | 2007-10-17 | — | — | EP | disclosed |
| EP-1623437-A1 | CONDUCTIVE CARBON NANOTUBE-POLYMER COMPOSITE | Carbon Nanotechnologies, Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004097853-A1 | CONDUCTIVE CARBON NANOTUBE-POLYMER COMPOSITE | CARBON NANOTECHNOLOGIES, INC. (US) | 2004-11-11 | — | — | WO | disclosed |
| WO-2002032473-A2 | ADHESIVE ATTACHMENT SYSTEM | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 2002-04-25 | — | — | WO | disclosed |