Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 6/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.44 |
| ▸ | GBA1 | P04062 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844214 | 0.97 | CHRNB2 (0.44) | CHRNB2CHRNA4GBA1KDM4ERECQL | |
| SCHEMBL17844247 | 0.90 | HTR1B (0.39) | KDM4ERECQLALDH1A1 | |
| SCHEMBL5184340 | 0.86 | GBA1 (0.35) | GBA1KDM4EALDH1A1USP2 | |
| SCHEMBL5186747 | 0.83 | PTPN2 (0.37) | RECQL | |
| SCHEMBL17844223 | 0.82 | DRD2 (0.41) | — | |
| SCHEMBL17844232 | 0.81 | DRD2 (0.44) | CHRNB2CHRNA4KDM4E | |
| SCHEMBL17844246 | 0.80 | HCRTR1 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL17844176 | 0.80 | ADORA3 (0.35) | — | |
| SCHEMBL17844178 | 0.80 | DRD4 (0.43) | KDM4EALDH1A1 | |
| SCHEMBL17844169 | 0.79 | SCN9A (0.36) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |