Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844249 | 0.90 | ACHE (0.50) | SIGMAR1ALDH1A1GAAACHEDRD4 | |
| SCHEMBL17844171 | 0.89 | MALT1 (0.47) | ACHEDRD4DRD2BCHE | |
| SCHEMBL17844164 | 0.86 | KAT2B (0.38) | CA12CA2CA9 | |
| SCHEMBL17844243 | 0.78 | PRKAA2 (0.43) | ACHEBCHE | |
| SCHEMBL3546550 | 0.75 | LMNA (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL17844145 | 0.74 | HRH3 (0.38) | ALDH1A1MEN1KMT2A | |
| SCHEMBL17844110 | 0.73 | MAOA (0.40) | SIGMAR1MEN1KMT2A | |
| SCHEMBL17844162 | 0.72 | HRH3 (0.41) | ALDH1A1 | |
| SCHEMBL1998987 | 0.71 | NR1H2 (0.48) | SIGMAR1ALDH1A1GAAHSD17B10ACHE | |
| SCHEMBL5316660 | 0.70 | METAP1 (0.49) | ALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |