Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844171 | 0.95 | MALT1 (0.47) | ACHEBCHEMALT1BACE1DRD2 | |
| SCHEMBL17844160 | 0.90 | SIGMAR1 (0.45) | ACHEBCHEGAAKMT2AMEN1 | |
| SCHEMBL17844164 | 0.85 | KAT2B (0.38) | MAPK1 | |
| SCHEMBL17844243 | 0.84 | PRKAA2 (0.43) | ACHEBCHEMAPT | |
| SCHEMBL3546550 | 0.78 | LMNA (0.42) | KDM4EKMT2AMEN1HTTLMNA | |
| SCHEMBL17844145 | 0.75 | HRH3 (0.38) | KDM4EKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL17844162 | 0.73 | HRH3 (0.41) | KDM4EMAPTALDH1A1 | |
| SCHEMBL9785716 | 0.72 | POLB (0.59) | ACHEBCHEKDM4EGAAKMT2A | |
| SCHEMBL28781788 | 0.70 | ACHE (0.59) | ACHEBCHEKDM4EGAAKMT2A | |
| SCHEMBL1998211 | 0.69 | ACHE (0.57) | ACHEBCHEMALT1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |