Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 6/20 | 0.47 |
| ▸ | DRD4 | P21917 | 6/20 | 0.47 |
| ▸ | BCHE | P06276 | 6/20 | 0.46 |
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | BACE1 | P56817 | 4/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844249 | 0.95 | ACHE (0.50) | MALT1DRD2DRD4BCHEACHE | |
| SCHEMBL17844160 | 0.89 | SIGMAR1 (0.45) | DRD2DRD4BCHEACHE | |
| SCHEMBL17844243 | 0.79 | PRKAA2 (0.43) | BCHEACHE | |
| SCHEMBL3546550 | 0.75 | LMNA (0.42) | — | |
| SCHEMBL17844145 | 0.73 | HRH3 (0.38) | — | |
| SCHEMBL2003262 | 0.71 | BCHE (0.50) | MALT1DRD2DRD4BCHEACHE | |
| SCHEMBL8259147 | 0.70 | BACE1 (0.64) | DRD2DRD4BCHEACHEBACE1 | |
| SCHEMBL2885290 | 0.70 | BACE1 (0.64) | DRD2DRD4BCHEACHEBACE1 | |
| SCHEMBL13761943 | 0.70 | BACE1 (0.64) | DRD2DRD4BCHEACHEBACE1 | |
| SCHEMBL331018 | 0.70 | BCHE (0.68) | MALT1DRD2DRD4BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |