Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 4/20 | 0.48 |
| ▸ | PTGS2 known ✓ | P35354 | 3/20 | 0.48 |
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.47 |
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.43 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.37 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | PHLPP2 | Q6ZVD8 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | BLVRB | P30043 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.47 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19125153 | 0.89 | PHLPP2 (0.48) | ALDH1A1PHLPP2PTGS1PTGS2CYP2C9 | |
| SCHEMBL19125147 | 0.89 | PHLPP2 (0.48) | ALDH1A1PHLPP2PTGS1PTGS2CYP2C9 | |
| SCHEMBL135508 | 0.84 | PLCG1 (0.61) | ALDH1A1PHLPP2PTGS1PTGS2CYP2C9 | |
| SCHEMBL428681 | 0.84 | PLCG1 (0.61) | ALDH1A1PHLPP2PTGS1PTGS2CYP2C9 | |
| Olsalazine SCHEMBL29454399 | 0.83 | MEN1 (0.66) | ALDH1A1PHLPP2PTGS1PTGS2CYP2C9 | |
| Olsalazine SCHEMBL29767 | 0.83 | MEN1 (0.66) | ALDH1A1PHLPP2PTGS1PTGS2CYP2C9 | |
| Olsalazine SCHEMBL3476110 | 0.83 | MEN1 (0.66) | ALDH1A1PHLPP2PTGS1PTGS2CYP2C9 | |
| SCHEMBL10784910 | 0.79 | MEN1 (0.59) | ALDH1A1PHLPP2PTGS1PTGS2CYP2C9 | |
| SCHEMBL27727543 | 0.78 | PHLPP2 (0.60) | ALDH1A1PHLPP2PTGS1PTGS2CYP2C9 | |
| Chrysamine G SCHEMBL15818024 | 0.77 | TDP1 (0.70) | ALDH1A1PHLPP2PTGS1PTGS2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160187730-A1 | Polymer Film With Geometrically Anisotropic Nanostructures | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-06-30 | — | — | US | claimed |
| US-10948774-B2 | Photoaligned quantum rod enhancement films | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2021-03-16 | — | — | US | disclosed |
| US-20190129252-A1 | PHOTOALIGNED QUANTUM ROD ENHANCEMENT FILMS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-05-02 | — | — | US | disclosed |
| US-20170205669-A1 | IMAGE DISPLAY DEVICE AND ORIENTED MATERIAL USED IN SAME | DIC CORPORATION (JP) | 2017-07-20 | — | — | US | disclosed |
| US-20160187730-A1 | Polymer Film With Geometrically Anisotropic Nanostructures | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-06-30 | — | — | US | disclosed |