SCHEMBL17873232

SCHEMBL17873232

COc1ccc(CCC(C)C(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.59
ALDH1A1 P00352 3/20 0.57
MMP3 P08254 2/20 0.53
F2RL1 P55085 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
HTT P42858 1/20 0.53
FFAR1 O14842 1/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
GAA P10253 1/20 0.48
RECQL P46063 1/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28126646 0.86 LDHA (0.68) LDHAALDH1A1F2RL1SMN1; SMN2HTT
SCHEMBL7676917 0.83 LDHA (0.59) LDHAALDH1A1F2RL1SMN1; SMN2HTT
SCHEMBL3739740 0.83 LDHA (0.59) LDHAALDH1A1F2RL1SMN1; SMN2HTT
SCHEMBL8283100 0.82 LDHA (0.73) LDHAMMP3FFAR1
SCHEMBL663059 0.82 LDHA (0.73) LDHAMMP3FFAR1
SCHEMBL14920749 0.82 TSHR (0.67) ALDH1A1MMP3F2RL1SMN1; SMN2HTT
SCHEMBL6950447 0.81 KIF11 (0.57) LDHAALDH1A1F2RL1SMN1; SMN2FFAR1
SCHEMBL6942606 0.81 KIF11 (0.57) LDHAALDH1A1F2RL1SMN1; SMN2FFAR1
SCHEMBL18071078 0.81 KIF11 (0.57) LDHAALDH1A1F2RL1SMN1; SMN2FFAR1
SCHEMBL8199902 0.81 LDHA (0.57) LDHAALDH1A1F2RL1SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12215088-B2 Method for the industrial production of 2-halo-4,6-dialkoxy-1,3,5-triazines and their use in the presence of amines CROSSING SRL (IT) 2025-02-04 US disclosed
US-20250026728-A1 METHOD FOR THE INDUSTRIAL PRODUCTION OF 2-HALO-4,6-DIALKOXY-1,3,5-TRIAZINES AND THEIR USE IN THE PRESENCE OF AMINES CROSSING SRL (IT) 2025-01-23 US disclosed
US-20210355091-A1 METHOD FOR THE INDUSTRIAL PRODUCTION OF 2-HALO-4,6-DIALKOXY-1,3,5-TRIAZINES AND THEIR USE IN THE PRESENCE OF AMINES CROSSING SRL (IT) 2021-11-18 US disclosed
US-11111221-B2 Method for the industrial production of 2-halo- 4,6-dialkoxy-l,3,5-triazines and their use in the presence of amines CROSSING SRL (IT) 2021-09-07 US disclosed
EP-3524596-B1 REAGENTS COMPRISING 2-HALO-4,6-DIALKOXY-1,3,5-TRIAZINES IN THE PRESENCE OF AMINES AND THEIR USE IN A STABILIZATION METHOD. CROSSING SRL (IT) 2020-09-09 EP disclosed
EP-3524596-A1 REAGENTS COMPRISING 2-HALO-4,6-DIALKOXY-1,3,5-TRIAZINES IN THE PRESENCE OF AMINES AND THEIR USE IN A STABILIZATION METHOD. Crossing S.r.l. (IT) 2019-08-14 EP disclosed
EP-3237390-B1 METHOD FOR THE INDUSTRIAL PRODUCTION OF 2-HALO-4,6-DIALKOXY-1,3,5-TRIAZINE AND THEIR USE IN THE PRESENCE OF AMINES CROSSING S R L (IT) 2019-05-08 EP disclosed
US-20190077774-A1 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONISTS HOPE CITY (US) 2019-03-14 US disclosed
US-20180370924-A1 METHOD FOR THE INDUSTRIAL PRODUCTION OF 2-HALO-4,6-DIALKOXY-1,3,5-TRIAZINES AND THEIR USE IN THE PRESENCE OF AMINES CROSSING SRL (IT) 2018-12-27 US disclosed
EP-3237390-A2 METHOD FOR THE INDUSTRIAL PRODUCTION OF 2-HALO-4,6-DIALKOXY-1,3,5-TRIAZINE AND THEIR USE IN THE PRESENCE OF AMINES Crossing S.r.l. (IT) 2017-11-01 EP disclosed
WO-2016103185-A2 METHOD FOR THE INDUSTRIAL PRODUCTION OF 2-HALO -4,6-DIALKOXY-1,3,5-TRIAZINES AND THEIR USE IN THE PRESENCE OF AMINES CROSSING SRL (IT) 2016-06-30 WO disclosed
CN-1582279-A Peroxisome-activated receptor agonists LILLY CO ELI (US) 2005-02-16 CN disclosed
CN-1437587-A Benzoxazepinones and their use as squalene synthetase inhibitors TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-08-20 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180370924-A1 METHOD FOR THE INDUSTRIAL PRODUCTION OF 2-HALO-4,6-DIALKOXY-1,3,5-TRIAZINES AND THEIR USE IN THE PRESENCE OF AMINES COL2A1, COL1A1, WIZ LDHA 4277/4885ALDH1A1 1828/4885MMP3 2293/4885
US-11111221-B2 Method for the industrial production of 2-halo- 4,6-dialkoxy-l,3,5-triazines and their use in the presence of amines COL2A1, WIZ, HDHD5 LDHA 3908/4885ALDH1A1 2094/4885MMP3 2203/4885
US-12215088-B2 Method for the industrial production of 2-halo-4,6-dialkoxy-1,3,5-triazines and their use in the presence of amines COL2A1, COL1A1, WIZ LDHA 4277/4885ALDH1A1 1828/4885MMP3 2293/4885
US-20190077774-A1 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONISTS PPARG, PPARA, PPARD LDHA 815/4885ALDH1A1 551/4885MMP3 2454/4885
US-20210355091-A1 METHOD FOR THE INDUSTRIAL PRODUCTION OF 2-HALO-4,6-DIALKOXY-1,3,5-TRIAZINES AND THEIR USE IN THE PRESENCE OF AMINES COL2A1, COL1A1, IDUA LDHA 4064/4885ALDH1A1 2244/4885MMP3 2447/4885
US-20250026728-A1 METHOD FOR THE INDUSTRIAL PRODUCTION OF 2-HALO-4,6-DIALKOXY-1,3,5-TRIAZINES AND THEIR USE IN THE PRESENCE OF AMINES COL2A1, COL1A1, COL14A1 LDHA 4244/4885ALDH1A1 1877/4885MMP3 1999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.