SCHEMBL1788985

SCHEMBL1788985

C=C(CCC=Cc1ccccc1OC)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 3/20 0.52
TFEB P19484 1/20 0.51
KDM4E B2RXH2 4/20 0.50
NPC1 O15118 3/20 0.50
MAPT P10636 3/20 0.50
LMNA P02545 3/20 0.50
RAB9A P51151 2/20 0.50
BCHE P06276 1/20 0.50
GRIK1 P39086 1/20 0.49
GRIK2 Q13002 1/20 0.49
GRIK3 Q13003 1/20 0.49
TRPA1 O75762 1/20 0.46
KMT2A Q03164 2/20 0.46
CYP3A4 P08684 2/20 0.46
MAPK1 P28482 1/20 0.46
ATM Q13315 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3993756 0.85 NFE2L2 (0.58) NFE2L2TFEBKDM4ENPC1MAPT
SCHEMBL3993752 0.85 NFE2L2 (0.58) NFE2L2TFEBKDM4ENPC1MAPT
SCHEMBL1793023 0.81 ALDH1A1 (0.42) KDM4ENPC1LMNARAB9AALDH1A1
SCHEMBL1787953 0.80 NFKB1 (0.49) NFE2L2KDM4ENPC1MAPTLMNA
SCHEMBL1788686 0.78 GSR (0.46) KDM4ENPC1MAPTLMNARAB9A
SCHEMBL1791129 0.78 HSD11B1 (0.47) MAPTBCHEKMT2ACYP3A4ATM
SCHEMBL8080168 0.78 LTB4R (0.54) NFE2L2TFEBKDM4ENPC1MAPT
SCHEMBL13939641 0.78 KDM4E (0.56) NFE2L2TFEBKDM4ENPC1MAPT
SCHEMBL8080171 0.78 LTB4R (0.54) NFE2L2TFEBKDM4ENPC1MAPT
SCHEMBL1788677 0.77 KDM4E (0.55) NFE2L2KDM4ENPC1RAB9AGRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed
US-7041416-B2 Photosensitive resin composition, transfer material, image forming method, color filter and producing method thereof and photomask and producing method thereof FUJI PHOTO FILM CO., LTD. (JP) 2006-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT PPOX, CRY2, HCCS NFE2L2 405/4885TFEB 3875/4885KDM4E 114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.