Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.65 |
| ▸ | GRM8 | O00222 | 1/20 | 0.58 |
| ▸ | GRM6 | O15303 | 1/20 | 0.58 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.58 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.58 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.58 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.58 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.58 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.58 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.58 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.58 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.58 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL10896399 | 0.95 | GSR (0.59) | GSRGRM8GRM6GRIN2DGRIN3B | |
| Lysine SCHEMBL3213815 | 0.92 | GSR (0.77) | GSRGRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL20971787 | 0.90 | GSR (0.65) | GSRGRM8GRM6GRIN2DGRIN3B | |
| Lysine SCHEMBL8000334 | 0.90 | GSR (0.80) | GSRGRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL21796040 | 0.90 | GSR (0.80) | GSRGRM8GRM6GRIN2DGRIN3B | |
| Lysine SCHEMBL890044 | 0.90 | GSR (0.80) | GSRGRM8GRM6GRIN2DGRIN3B | |
| Lysine SCHEMBL7258645 | 0.90 | GSR (0.80) | GSRGRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL2415481 | 0.90 | GSR (0.80) | GSRGRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL1079951 | 0.90 | GSR (0.80) | GSRGRM8GRM6GRIN2DGRIN3B | |
| Lysine SCHEMBL8000337 | 0.90 | GSR (0.80) | GSRGRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164799-A | Composition comprising ethers synthesized from fatty alcohols and glycerol | 日本乐敦制药株式会社 | 2021-07-23 | — | — | CN | disclosed |
| US-10668091-B2 | Antibacterial agent against multidrug-resistant gram-positive bacteria and external agent | KEWPIE CORPORATION (JP) | 2020-06-02 | — | — | US | disclosed |
| CN-105899544-B | Hyaluronic acid and/or salt thereof, method for producing same, and food, cosmetic and pharmaceutical containing same | 丘比株式会社 | 2019-09-20 | — | — | CN | disclosed |
| CN-105682663-B | Multiple drug-resistant gram-positive bacteria antibacterial agent and external agent | 丘比株式会社 | 2019-08-02 | — | — | CN | disclosed |
| EP-3000858-B1 | GELLANT | AJINOMOTO KK (JP) | 2019-02-13 | — | — | EP | disclosed |
| US-20180289726-A1 | ANTIBACTERIAL AGENT AGAINST MULTIDRUG-RESISTANT GRAM-POSITIVE BACTERIA AND EXTERNAL AGENT | KEWPIE CORP (JP) | 2018-10-11 | — | — | US | disclosed |
| US-20160303148-A1 | Multidrug-Resistant Gram-Positive Bacteria Antibacterial Agent and Topical Agent | KEWPIE CORPORATION (JP) | 2016-10-20 | — | — | US | disclosed |
| EP-3075382-A1 | MULTIDRUG-RESISTANT GRAM-POSITIVE BACTERIA ANTIBACTERIAL AGENT AND TOPICAL AGENT | Kewpie Corporation (JP) | 2016-10-05 | — | — | EP | disclosed |
| CN-105682663-A | Multiple drug-resistant gram-positive bacteria antibacterial agent and external agent | 丘比株式会社 | 2016-06-15 | — | — | CN | disclosed |
| EP-3000858-A1 | GELLANT | Ajinomoto Co., Inc. (JP) | 2016-03-30 | — | — | EP | disclosed |
| CN-102770459-B | Modify hyaluronic acid and/or its salt and manufacture method thereof and the makeup containing it | KEWPIE CORP. (JP) | 2016-01-20 | — | — | CN | disclosed |
| CN-105229109-A | Gelating agent | AJINOMOTO KK | 2016-01-06 | — | — | CN | disclosed |
| US-20110123671-A1 | ADDITIVE FOR LIVESTOCK FEED AND FEED COMPOSITION FOR LIVESTOCK | AJINOMOTO CO., INC. (JP) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160303148-A1 | Multidrug-Resistant Gram-Positive Bacteria Antibacterial Agent and Topical Agent | CUTA, LCT, MGLL | GSR 1698/4885GRM8 3480/4885GRM6 3373/4885 |
| US-20180289726-A1 | ANTIBACTERIAL AGENT AGAINST MULTIDRUG-RESISTANT GRAM-POSITIVE BACTERIA AND EXTERNAL AGENT | GANAB, ABCC1, LGMN | GSR 926/4885GRM8 3072/4885GRM6 3098/4885 |
| US-10668091-B2 | Antibacterial agent against multidrug-resistant gram-positive bacteria and external agent | GANAB, ABCC1, LGMN | GSR 926/4885GRM8 3072/4885GRM6 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.