Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 known ✓ | P41231 | 4/20 | 0.66 |
| ▸ | P2RY4 known ✓ | P51582 | 2/20 | 0.66 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.62 |
| ▸ | P2RY6 known ✓ | Q15077 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | GLA | P06280 | 1/20 | 0.81 |
| ▸ | ST6GAL1 | P15907 | 10/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MTOR | P42345 | 1/20 | 0.62 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.62 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.62 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.62 |
| ▸ | NT5E | P21589 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356399 | 1.00 | TSHR (0.81) | TSHRGLAST6GAL1P2RY2P2RY4 | |
| Potassium Ion SCHEMBL10585798 | 0.99 | TSHR (0.80) | TSHRGLAST6GAL1P2RY2P2RY4 | |
| Cystetine Triphosphate SCHEMBL9101211 | 0.98 | TSHR (0.81) | TSHRGLAST6GAL1P2RY2P2RY4 | |
| Cystetine Triphosphate SCHEMBL31405617 | 0.97 | TSHR (0.80) | TSHRGLAST6GAL1P2RY2P2RY4 | |
| Cystetine Triphosphate SCHEMBL10826769 | 0.97 | TSHR (0.80) | TSHRGLAST6GAL1P2RY2P2RY4 | |
| SCHEMBL11616961 | 0.94 | TSHR (0.78) | TSHRGLAST6GAL1P2RY2P2RY4 | |
| Cystetine Triphosphate SCHEMBL2194120 | 0.92 | TSHR (0.79) | TSHRGLAST6GAL1P2RY2P2RY4 | |
| Cystetine Triphosphate SCHEMBL11613107 | 0.92 | TSHR (0.79) | TSHRGLAST6GAL1P2RY2P2RY4 | |
| Choline SCHEMBL503814 | 0.92 | TSHR (0.81) | TSHRGLAST6GAL1P2RY2P2RY4 | |
| Cytarabine 5'-Phosphate SCHEMBL859798 | 0.92 | TSHR (0.74) | TSHRGLAST6GAL1P2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115613085-A | Brush silver-plating alloy plating solution for repairing silver-plated layer of open-type isolating switch and preparation method thereof | 国网山东省电力公司电力科学研究院 | 2023-01-17 | — | — | CN | claimed |
| CN-101538300-B | Salting-out and dissolution crystallization method of citicoline | NANJING TECH UNIVERSITY (CN) | 2011-11-30 | — | — | CN | claimed |
| CN-101538300-A | Salting-out and dissolution crystallization method of citicoline | NANJING UNIVERSITY OF TECHNOLOGY | 2009-09-23 | — | — | CN | claimed |
| CN-101130797-A | Ubelin manufacturing technique | JIAN ZHANG (CN) | 2008-02-27 | — | — | CN | claimed |
| CN-114099548-B | Human neural stem cell preparation and preparation method thereof | 领航干细胞再生医学工程有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115896217-A | Feed supplementing process for improving fermentation level of tulathromycin | 内蒙古中牧生物药业有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115613085-A | Brush silver-plating alloy plating solution for repairing silver-plated layer of open-type isolating switch and preparation method thereof | 国网山东省电力公司电力科学研究院 | 2023-01-17 | — | — | CN | disclosed |
| CN-115397400-A | Sunflower phospholipid composition containing phosphatidylcholine | 利珀德有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-107737339-B | Calcium phosphate-biomolecule composite material and preparation method thereof | 中国科学院上海硅酸盐研究所 | 2021-06-15 | — | — | CN | disclosed |
| CN-101906126-B | Method for separating and purifying citicoline by hydrophobic chromatography | NANJING UNIVERSITY OF TECHNOLOGY | 2012-04-25 | — | — | CN | disclosed |
| CN-101538300-B | Salting-out and dissolution crystallization method of citicoline | NANJING TECH UNIVERSITY (CN) | 2011-11-30 | — | — | CN | disclosed |
| CN-101906126-A | Method for separating and purifying citicoline by hydrophobic chromatography | NANJING UNIVERSITY OF TECHNOLOGY | 2010-12-08 | — | — | CN | disclosed |
| CN-101538300-A | Salting-out and dissolution crystallization method of citicoline | NANJING UNIVERSITY OF TECHNOLOGY | 2009-09-23 | — | — | CN | disclosed |
| CN-101130797-A | Ubelin manufacturing technique | JIAN ZHANG (CN) | 2008-02-27 | — | — | CN | disclosed |
| US-7223857-B2 | Chain-shortened polynucleotide and method for preparation thereof | NIPPON SHINYAKU CO., LTD. (JP) | 2007-05-29 | — | — | US | disclosed |
| EP-1153931-B1 | SHORTENED-CHAIN POLYNUCLEOTIDES AND PROCESS FOR THE PREPARATION THEREOF | NIPPON SHINYAKU CO LTD (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-20040235044-A1 | Chain-shortened polynucleotide and method for preparation thereof | MATSUYAMA SHINJI (JP) | 2004-11-25 | — | — | US | disclosed |
| US-6780429-B1 | WITH 2'-5' PHOSPHODIESTER BOND CONTENT UP TO 3%; MAINTAINS PHARMACOLOGICAL ACTION WHILE REDUCING TOXICITY | NIPPON SHINYAKU CO., LTD. (JP) | 2004-08-24 | — | — | US | disclosed |
| EP-1153931-A1 | SHORTENED-CHAIN POLYNUCLEOTIDES AND PROCESS FOR THE PREPARATION THEREOF | Nippon Shinyaku Co., Ltd. (JP) | 2001-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235044-A1 | Chain-shortened polynucleotide and method for preparation thereof | POLN, POLRMT, POLI | P2RY2 461/4885P2RY4 416/4885THRB 4339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.