Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | CFB | P00751 | 3/20 | 0.40 |
| ▸ | PGR | P06401 | 3/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1799535 | 0.88 | AR (0.42) | ARKDM4EUSP2ALDH1A1TTBK1 | |
| SCHEMBL22396562 | 0.81 | ALDH1A1 (0.44) | ARKDM4EUSP2ALDH1A1TTBK1 | |
| SCHEMBL24476682 | 0.78 | AR (0.54) | ARKDM4EUSP2ALDH1A1PGR | |
| SCHEMBL1794793 | 0.78 | PGK1 (0.45) | ARALKL3MBTL1FNTAFNTB | |
| SCHEMBL17672911 | 0.78 | ALK (0.42) | KDM4EALDH1A1TTBK1ALKL3MBTL1 | |
| SCHEMBL21880257 | 0.78 | LMNA (0.43) | KDM4EUSP2ALDH1A1TTBK1LMNA | |
| SCHEMBL1798585 | 0.75 | PGK1 (0.45) | ARALKL3MBTL1FNTAFNTB | |
| SCHEMBL1797171 | 0.74 | AR (0.49) | ARKDM4EUSP2ALDH1A1PGR | |
| SCHEMBL1795798 | 0.74 | PDK1 (0.43) | ALKEGFR | |
| SCHEMBL6357681 | 0.73 | ASIC3 (0.39) | TTBK1ALKLMNAL3MBTL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951827-B2 | Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2011-05-31 | — | — | US | disclosed |
| US-20060264487-A1 | Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles | TIDWELL RICHARD R | 2006-11-23 | — | — | US | disclosed |
| EP-1719767-A1 | Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles | The University of North Carolina at Chapel Hill (US) | 2006-11-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264487-A1 | Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles | PFAS, DHPS, DDO | AR 4850/4885KDM4E 2058/4885USP2 4114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.