Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOC | P08134 | 4/20 | 0.53 |
| ▸ | RHOA | P61586 | 4/20 | 0.53 |
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | CHUK | O15111 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | MYLK | Q15746 | 1/20 | 0.50 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1799415 | 0.89 | MPO (0.55) | RHOCRHOATMPRSS4MEN1KMT2A | |
| SCHEMBL1797516 | 0.85 | ALDH1A1 (0.50) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL1015370 | 0.81 | KDM4E (0.60) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL1796795 | 0.81 | LMNA (0.45) | MEN1KMT2AMAPTGAAHTT | |
| SCHEMBL1015454 | 0.80 | ALDH1A1 (0.51) | MEN1KMT2AP2RX1MAPTGAA | |
| SCHEMBL7125633 | 0.80 | ALDH1A1 (0.62) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL418801 | 0.79 | SERPINE1 (0.52) | RHOCRHOATMPRSS4MEN1KMT2A | |
| SCHEMBL9674267 | 0.78 | ALDH1A1 (0.65) | MEN1KMT2AMAPTGAAHTT | |
| SCHEMBL1018800 | 0.78 | GRIK1 (0.47) | MEN1KMT2AMAPTGAANPSR1 | |
| SCHEMBL1015672 | 0.78 | ALDH1A1 (0.58) | MEN1KMT2AMAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951806-B2 | Plasminogen activator inhibitor-1 inhibitor | RENASCIENCE CO., LTD. (JP) | 2011-05-31 | — | — | US | disclosed |
| US-20090124620-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | RENASCIENCE CO., LTD. (JP) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124620-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | SERPINE1, SERPINC1, SERPINB1 | RHOC 3393/4885RHOA 751/4885TMPRSS4 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.