SCHEMBL1801131

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1800853	0.86	ALDH1A1 (0.49)	RIPK1ALDH1A1KDM4EPOLBMAPT
	SCHEMBL1802356	0.86	P2RX7 (0.36)	ALDH1A1RAB9ALMNA
	SCHEMBL1802473	0.80	RIPK1 (0.50)	RIPK1ALDH1A1KDM4EKMT2AMEN1
	SCHEMBL1800533	0.79	ALDH1A1 (0.47)	RIPK1ALDH1A1KDM4EPOLBMAPT
	SCHEMBL1803894	0.79	RIPK1 (0.51)	RIPK1ALDH1A1MAPTKMT2AMEN1
	SCHEMBL5156459	0.79	ALDH1A1 (0.48)	RIPK1ALDH1A1KDM4EKMT2AMEN1
	SCHEMBL1802840	0.78	ALDH1A1 (0.47)	RIPK1ALDH1A1KDM4EPOLBMAPT
	SCHEMBL4001000	0.78	L3MBTL1 (0.43)	RIPK1ALDH1A1KDM4EKMT2AMEN1
	SCHEMBL1802733	0.78	RIPK1 (0.54)	RIPK1ALDH1A1KDM4EPOLBKMT2A
	SCHEMBL1802555	0.78	USP2 (0.52)	RIPK1ALDH1A1POLBMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.