SCHEMBL180125

SCHEMBL180125

[CH]1C=Cc2cc3c(cc21)CCC3

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.34
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21244341 0.98 CDC25B (0.33) CDC25BGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL814717 0.95 CDC25B (0.39) CDC25BALDH1A1
SCHEMBL814603 0.93 CDC25B (0.38) CDC25BALDH1A1
SCHEMBL817303 0.93 CDC25B (0.38) CDC25BALDH1A1
SCHEMBL814636 0.93 CDC25B (0.38) CDC25BALDH1A1
SCHEMBL815102 0.93 CDC25B (0.38) CDC25BALDH1A1
SCHEMBL817127 0.93 CDC25B (0.38) CDC25BALDH1A1
SCHEMBL814432 0.93 CDC25B (0.38) CDC25BALDH1A1
SCHEMBL816223 0.93 CDC25B (0.38) CDC25BALDH1A1
SCHEMBL814735 0.93 CDC25B (0.38) CDC25BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218282-A1 ETHYLENE-PROPYLENE BRANCHED COPOLYMERS USED AS VISCOSITY MODIFIERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-07-04 US disclosed
WO-2024059737-A2 CATALYST SYSTEMS AND PROCESSES FOR CYCLIC POLY ALPHA-OLEFINS ExxonMobil Technology and Engineering Company (US) 2024-03-21 WO disclosed
CN-117597420-A Ethylene-propylene branched copolymers useful as viscosity modifiers 埃克森美孚化学专利公司 2024-02-23 CN disclosed
US-11766669-B2 Hexahydrocyclopenta[e]-as-indacen-1-yl and octahydrobenzo[e]-as-indacen-1-yl based catalyst complexes and process for use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-09-26 US disclosed
US-11661465-B2 Dimer selective metallocene catalysts, non-aromatic hydrocarbon soluble activators, and processes to produce poly alpha-olefin oligmers therewith EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-05-30 US disclosed
CN-111868106-B Catalyst system and process for poly-alpha-olefins having high vinylidene content 埃克森美孚化学专利公司 2023-02-17 CN disclosed
CN-111417657-B Asymmetric ansa-metallocene catalyst compounds for the preparation of polyolefins having broad molecular weight distribution 埃克森美孚化学专利公司 2022-11-25 CN disclosed
US-11492425-B2 Metallocene catalyst compositions and polymerization process therewith EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-11-08 US disclosed
CN-112703210-B Preparation of bimodal rubbers, thermoplastic vulcanizates, and articles made therefrom 埃克森美孚化学专利公司 2022-10-28 CN disclosed
CN-114845980-A Dimer-selective metallocene catalyst, non-aromatic hydrocarbon soluble activator and method for preparing poly alpha-olefin oligomer using the same 埃克森美孚化学专利公司 2022-08-02 CN disclosed
US-20070135595-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS, INC. 2007-06-14 US disclosed
US-20070135594-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
US-20070135623-A1 Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
US-20070135593-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
US-20060183874-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-08-17 US disclosed
US-20060160967-A1 Halogen substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-07-20 US disclosed
US-20060160968-A1 Process for producing substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-07-20 US disclosed
WO-2006065843-A2 HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed
WO-2006065844-A2 PROCESS FOR PRODUCING SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed
WO-2006065906-A2 HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135623-A1 Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization OPRM1, POLM, AP1M1 CDC25B 2652/4885GRIN2D 1147/4885GRIN3B 651/4885
US-20060183874-A1 Halogen substituted metallocene compounds for olefin polymerization B2M, CDYL, MLX CDC25B 375/4885GRIN2D 666/4885GRIN3B 1303/4885
US-20070135594-A1 Halogen substituted metallocene compounds for olefin polymerization MLX, AP1M1, AP2M1 CDC25B 1240/4885GRIN2D 1444/4885GRIN3B 851/4885
US-20070135595-A1 Halogen substituted metallocene compounds for olefin polymerization AP2M1, AP1M1, CPNE4 CDC25B 3021/4885GRIN2D 2713/4885GRIN3B 2244/4885
US-11492425-B2 Metallocene catalyst compositions and polymerization process therewith TERT, MDM4, PCBP1 CDC25B 1050/4885GRIN2D 2099/4885GRIN3B 910/4885
US-11766669-B2 Hexahydrocyclopenta[e]-as-indacen-1-yl and octahydrobenzo[e]-as-indacen-1-yl based catalyst complexes and process for use thereof MLX, ZYX, TXN CDC25B 4328/4885GRIN2D 594/4885GRIN3B 1220/4885
US-20070135593-A1 Halogen substituted metallocene compounds for olefin polymerization ZKSCAN2, ZRANB2, ZC3H18 CDC25B 1983/4885GRIN2D 1081/4885GRIN3B 434/4885
US-20060160967-A1 Halogen substituted metallocene compounds for olefin polymerization OR10J3, ZRANB2, SLC39A3 CDC25B 2255/4885GRIN2D 1733/4885GRIN3B 383/4885
US-11661465-B2 Dimer selective metallocene catalysts, non-aromatic hydrocarbon soluble activators, and processes to produce poly alpha-olefin oligmers therewith NONO, TPR, ZNF787 CDC25B 4125/4885GRIN2D 3406/4885GRIN3B 2219/4885
US-20060160968-A1 Process for producing substituted metallocene compounds for olefin polymerization OSBP, OSBPL3, OSBP2 CDC25B 1457/4885GRIN2D 3295/4885GRIN3B 1400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.