Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18036657 | 0.89 | L3MBTL1 (0.46) | ALDH1A1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL5240191 | 0.86 | L3MBTL1 (0.49) | SMN1; SMN2L3MBTL1ADRA1AADRA1BADRA1D | |
| SCHEMBL7961982 | 0.85 | L3MBTL1 (0.51) | ALDH1A1SMN1; SMN2L3MBTL1ADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL28299875 | 0.81 | SLC6A9 (0.47) | ALDH1A1SMN1; SMN2ADRA1AADRA1BADRA1D | |
| SCHEMBL18036644 | 0.81 | SLC6A9 (0.47) | ALDH1A1SMN1; SMN2ADRA1AADRA1BADRA1D | |
| SCHEMBL6184895 | 0.80 | AKR1C3 (0.61) | ALDH1A1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL7835975 | 0.80 | RAB9A (0.46) | ALDH1A1L3MBTL1ADRA1AADRA1BADRA1D | |
| SCHEMBL24712880 | 0.77 | DRD2 (0.59) | ALDH1A1ADRA1AADRA1BADRA1DCYP3A4 | |
| SCHEMBL5473619 | 0.77 | SLC6A2 (0.62) | ADRA1AADRA1BADRA1DLMNACYP3A4 | |
| SCHEMBL5234580 | 0.76 | GAA (0.46) | ALDH1A1SMN1; SMN2L3MBTL1ADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083588-B1 | AROMATIC HETEROCYCLIC COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS | SUNSHINE LAKE PHARMA CO LTD (CN) | 2020-12-09 | — | — | EP | disclosed |
| US-9663498-B2 | Aromatic heterocyclic compounds and their application in pharmaceuticals | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-05-30 | — | — | US | disclosed |
| US-20160251339-A1 | AROMATIC HETEROCYCLIC COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160251339-A1 | AROMATIC HETEROCYCLIC COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS | MAPT, APP, PSEN1 | ALDH1A1 1342/4885SMN1; SMN2 663/4885L3MBTL1 4730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.