Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5240191 | 0.88 | L3MBTL1 (0.49) | L3MBTL1ADRA1AADRA1BADRA1DTSHR | |
| SCHEMBL18036632 | 0.85 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1ADRA1AADRA1BADRA1D | |
| SCHEMBL24712880 | 0.82 | DRD2 (0.59) | ALDH1A1ADRA1AADRA1BADRA1DCYP3A4 | |
| SCHEMBL5234580 | 0.81 | GAA (0.46) | L3MBTL1ALDH1A1ADRA1AADRA1BADRA1D | |
| SCHEMBL7835975 | 0.80 | RAB9A (0.46) | L3MBTL1ALDH1A1NPSR1ADRA1AADRA1B | |
| SCHEMBL7341055 | 0.79 | TSHR (0.60) | L3MBTL1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7947390 | 0.79 | LMNA (0.57) | ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7793932 | 0.79 | AKR1C3 (0.68) | L3MBTL1ALDH1A1NPSR1TSHRSMN1; SMN2 | |
| SCHEMBL24712881 | 0.78 | ADRA1A (0.49) | L3MBTL1ALDH1A1ADRA1AADRA1BADRA1D | |
| SCHEMBL7719064 | 0.78 | ADRA1A (0.51) | ALDH1A1ADRA1AADRA1BADRA1DCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271234-B1 | DERIVATIVES WHICH BIND TO SEROTONERGIC RECEPTORS; TREATING DISORDERS OF THE LOWER URINARY TRACT | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2001-08-07 | — | — | US | disclosed |