Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 4/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL18062300 | 0.98 | LMNA (0.42) | LMNATP53CA1CYP2D6SPHK1 | |
| Potassium Ion SCHEMBL8824224 | 0.98 | LMNA (0.47) | LMNATP53CA1CYP2D6SPHK1 | |
| SCHEMBL1413951 | 0.96 | LMNA (0.43) | LMNATP53CA1CYP2D6SPHK1 | |
| SCHEMBL1414118 | 0.96 | LMNA (0.43) | LMNATP53CA1CYP2D6SPHK1 | |
| SCHEMBL3259690 | 0.96 | LMNA (0.43) | LMNATP53CA1CYP2D6SPHK1 | |
| SCHEMBL18986934 | 0.94 | LMNA (0.47) | LMNATP53CA1CYP2D6SPHK1 | |
| SCHEMBL7469371 | 0.94 | LMNA (0.47) | LMNATP53CA1CYP2D6SPHK1 | |
| SCHEMBL135873 | 0.94 | LMNA (0.47) | LMNATP53CA1CYP2D6SPHK1 | |
| SCHEMBL185844 | 0.94 | LMNA (0.47) | LMNATP53CA1CYP2D6SPHK1 | |
| SCHEMBL8824223 | 0.94 | LMNA (0.47) | LMNATP53CA1CYP2D6SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678163-B | Nanoemulsion comprising sulfoalkyl esters and/or amides of fatty acids in aqueous phase | 联合利华知识产权控股有限公司 | 2022-06-17 | — | — | CN | disclosed |
| US-11234908-B2 | Nanoemulsions comprising sulfoalkyl ester and/or amide of fatty acids in aqueous phase | CONOPCO, INC. (US) | 2022-02-01 | — | — | US | disclosed |
| US-20210128421-A1 | NANOEMULSIONS COMPRISING SULFOALKYL ESTER AND/OR AMIDE OF FATTY ACIDS IN AQUEOUS PHASE | CONOPCO, INC., D/B/A UNILEVER (US) | 2021-05-06 | — | — | US | disclosed |
| EP-3612150-B1 | NANOEMULSIONS COMPRISING SULFOALKYL ESTER AND/OR AMIDE OF FATTY ACIDS IN AQUEOUS PHASE | UNILEVER PLC (GB) | 2020-08-19 | — | — | EP | disclosed |
| EP-3612150-A1 | NANOEMULSIONS COMPRISING SULFOALKYL ESTER AND/OR AMIDE OF FATTY ACIDS IN AQUEOUS PHASE | Unilever Plc. (GB) | 2020-02-26 | — | — | EP | disclosed |
| CN-110678163-A | Nanoemulsion comprising sulfoalkyl esters and/or amides of fatty acids in aqueous phase | 荷兰联合利华有限公司 | 2020-01-10 | — | — | CN | disclosed |
| US-10376456-B2 | Concentrated and self-preserving compositions of mild surfactants for transparent and skin-pH personal care formulations | GALAXY SURFACTANT (IN) | 2019-08-13 | — | — | US | disclosed |
| US-20190167554-A1 | CONCENTRATED AND SELF-PRESERVING COMPOSITIONS OF MILD SURFACTANTS FOR TRANSPARENT AND SKIN-pH PERSONAL CARE FORMULATIONS | GNA Surfactants Ltd. (IN) | 2019-06-06 | — | — | US | disclosed |
| WO-2018192761-A1 | NANOEMULSIONS COMPRISING SULFOALKYL ESTER AND/OR AMIDE OF FATTY ACIDS IN AQUEOUS PHASE | UNILEVER PLC (GB) | 2018-10-25 | — | — | WO | disclosed |
| WO-2016147196-A1 | CONCENTRATED AND SELF-PRESERVING COMPOSITIONS OF MILD SURFACTANTS FOR TRANSPARENT AND SKIN-PH PERSONAL CARE FORMULATIONS | GALAXY SURFACTANTS LTD. (IN) | 2016-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10376456-B2 | Concentrated and self-preserving compositions of mild surfactants for transparent and skin-pH personal care formulations | CUTA, KAT7, KCNN3 | LMNA 3845/4885TP53 2023/4885CA1 1811/4885 |
| US-20190167554-A1 | CONCENTRATED AND SELF-PRESERVING COMPOSITIONS OF MILD SURFACTANTS FOR TRANSPARENT AND SKIN-pH PERSONAL CARE FORMULATIONS | CUTA, KAT7, KCNN3 | LMNA 3771/4885TP53 1886/4885CA1 1775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.